product summary
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company name :
NKMAX
product type :
protein
product name :
Recombinant canine IL-5 protein
catalog :
ATGP3985
quantity :
10 ug
price :
140 USD
more info or order :
product information
Product Type :
Proteins
Item Name :
Recombinant canine IL-5 protein
Domain :
22-134aa
Catalog number (SKU) :
ATGP3985
NCBI :
NP_001006951
Description :
IL-5, also known as interleukin-5, is a member of the hematopoietin receptor superfamily and is comprised of a cytokine-specific alpha chain and the common beta chain that is shared among these cytokines for signaling. Through binding to the IL-5 receptor, IL-5 stimulates B cell growth and increases immunoglobulin secretion. It related hematopoietic cytokines that are important for allergic inflammation. It is a lineage-specific cytokine for eosinophilpoiesis and plays an important part in diseases associated with increased eosinophils, such as asthma. Recombinant canine IL-5, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques
Alternative Names :
Interleukin-5, Eosinophil differentiation factor, T-cell replacing factor, TRF, EDF
Concentration :
0.25mg/ml (determined by Absorbance at 280nm)
Formulation :
Liquid. In Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Martinez-Moczygemba M., et al. (2003) J Allergy Clin Immunol. 112:653-665.;; Milburn MV., et al. (1993) Nature. 363:172-176.
Purity :
> 90% by SDS - PAGE
Bioactivity Comment Only :
Measured in a cell proliferation assay using TF-1 human erythroleukemic cell. The ED50 range ≤ 15 ng/ml.
Applications :
SDS-PAGE, Bioactivity
Antigen Species :
Canine
Gene Category :
Immunology, Cancer
Molecular Weight :
13.9kDa (119aa)
Endotoxin :
< 1 EU per 1ug of protein (determined by LAL method)
Bioactivity Comment and Pics :
Canine IL-5 in a cell proliferation assay using TF-1 human erythroleukemic cell. The ED50 range ≤ 15 ng/ml.
Amino Acid Sequence :
VENPMNRLVA ETLTLLSTHR TWLIGDGNLM IPTPENKNHQ LCIKEVFQGI DTLKNQTAHG EAVDKLFQNL SLIKEHIERQ KKRCAGERWR VTKFLDYLQV FLGVINTEWT PES
Tag :
His-Tag
Expression System :
Baculovirus
Predicted nterm :
Val 22
Product Type Name :
Recombinant Protein
UniProt No. :
Q95J76
Internal Search Terms :
B cell growth factor II, B-cell growth factor II, BCGF I, BCGF II, BCGFI, BCGF-I, BCGFII, BCGF-II, EDF, Eosinophil differentiation factor, IL 5, IL5, IL-5, Interleukin 5, Interleukin5, Interleukin-5, T cell replacing factor, T-cell replacing factor, TRF, ATGP3985-10ug, ATGP3985-20ug, ATGP3985-50ug, ATGP3985-100ug, ATGP3985-250ug, ATGP3985-500ug, ATGP3985-1mg, ATGP3985-010, ATGP3985-020, ATGP3985-050, ATGP3985-100, ATGP3985-250, ATGP3985-500, ATGP3985-01M
more info or order :
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.