product summary
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company name :
NKMAX
product type :
protein
product name :
Recombinant mouse sFRP-2/SFRP2 protein
catalog :
ATGP3973
quantity :
10 ug
price :
160 USD
more info or order :
product information
Product Type :
Proteins
Item Name :
Recombinant mouse sFRP-2/SFRP2 protein
Domain :
25-295aa
Catalog number (SKU) :
ATGP3973
NCBI :
NP_033170.1
Description :
sFRP-2, also known as Secreted apoptosis-related protein 1, is a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. sFRP-2 can exert either positive or negative effects on Wnt signaling. At physiological concentrations, it also inhibits BMP-induced effects. It plays a variety of roles during tissue morphogenesis including inhibition of the planar cell polarity pathway and myoblast and osteoblast differentiation. It is also expressed in multiple myeloma and glioma in which it promotes tumorigenicity. Recombinant mouse sFRP-2, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Alternative Names :
sFRP-2, sFRP2, Secreted frizzled-related protein 2, Secreted apoptosis-related protein 1, SDF-5, Sdf5, sdf, SARP-1, SARP1, Protein SDF5, FRP-2secreted apoptosis related protein 1, AI851596
Concentration :
0.25mg/ml (determined by absorbance at 280nm)
Formulation :
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 100mM NaCl, 20% glycerol
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Alfaro, M.P. et al. (2010) J. Biol. Chem. 285:35645-35653;; He, W. et al. (2010) Proc. Natl. Acad. Sci. 107:21110-21115;;
Purity :
> 90% by SDS-PAGE
Applications :
SDS-PAGE
Antigen Species :
Mouse
Gene Category :
Signal Transduction
Molecular Weight :
32.1kDa (280aa)
Endotoxin :
< 1 EU per 1ug of protein (determined by LAL method)
Amino Acid Sequence :
LFLFGQP DFSYKRSNCK PIPANLQLCH GIEYQNMRLP NLLGHETMKE VLEQAGAWIP LVMKQCHPDT KKFLCSLFAP VCLDDLDETI QPCHSLCVQV KDRCAPVMSA FGFPWPDMLE CDRFPQDNDL CIPLASSDHL LPATEEAPKV CEACKTKNED DNDIMETLCK NDFALKIKVK EITYINRDTK IILETKSKTI YKLNGVSERD LKKSVLWLKD SLQCTCEEMN DINAPYLVMG QKQGGELVIT SVKRWQKGQR EFKRISRSIR KLQC
Tag :
His-Tag
Expression System :
Baculovirus
Predicted nterm :
Ala
Product Type Name :
Recombinant Protein
UniProt No. :
P97299
Internal Search Terms :
,ATGP3973-10ug,ATGP3973-20ug,ATGP3973-50ug,ATGP3973-100ug,ATGP3973-250ug,ATGP3973-500ug,ATGP3973-1mg,ATGP3973-10,ATGP3973-20,ATGP3973-50,ATGP3973-100,ATGP3973-250,ATGP3973-500,ATGP3973-1
more info or order :
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.