Recombinant mouse OX40/TNFRSF4 protein | NKMAX ATGP3971 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant mouse OX40/TNFRSF4 protein

catalog :

ATGP3971

quantity :

10 ug

price :

120 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant mouse OX40/TNFRSF4 protein

Domain :

20-211aa

Catalog number (SKU) :

ATGP3971

NCBI :

NP_035789.1

Description :

TNFRSF4, also known as CD134, is a member of the TNFR-superfamily of receptors. This protein is a receptor for TNFSF4/OX40L/GP34 and a costimulatory molecule implicated in long-term T-cell immunity. OX40-OX40L interactions regulate antigen-specific T-cell expansion and survival, cytokine production. It also modulates cytokine receptor signalling. Therefore the interaction between TNFRSF4 and CD40L plays a key role in the development of multiple imflammatry and autoimmune disease. It has been implicated in the pathologic cytokine storm associated with certain viral infections, including the H5N1 bird flu. Recombinant mouse OX40/TNFRSF4 , fused to hIgG-His-tag at C-terminus, was expressed in HEK293 cell and purified by using conventional chromatography techniques.

Alternative Names :

Tumor necrosis factor receptor superfamily member 4, TNFRSF4, ACT35, CD134, IMD16, OX40, TXGP1L, ACT35 antigen, OX40L receptor, TAX transcriptionally-activated glycoprotein 1 receptor

Concentration :

0.25mg/ml (determined by Absorbance at 280nm)

Formulation :

Liquid. In Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Schreiber TH, et al, (2012) J Immunol. 189:3311-3318.;; Webb GJ, et al, (2016) Clin Rev Allergy Immunol. 50:312-332.;; Zhou B, et al, (2020) Transplant Proc. 52:398-405.;;

Purity :

> 95% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Mouse

Gene Category :

Immunology

Molecular Weight :

48.6kDa (435aa)

Endotoxin :

< 1 EU per 1ug of protein (determined by LAL method)

Amino Acid Sequence :

VTARRL NCVKHTYPSG HKCCRECQPG HGMVSRCDHT RDTLCHPCET GFYNEAVNYD TCKQCTQCNH RSGSELKQNC TPTQDTVCRC RPGTQPRQDS GYKLGVDCVP CPPGHFSPGN NQACKPWTNC TLSGKQTRHP ASDSLDAVCE DRSLLATLLW ETQRPTFRPT TVQSTTVWPR TSELPSPPTL VTPEGP

Tag :

hIgG-His-Tag

Expression System :

HEK293

Predicted nterm :

Asp

Product Type Name :

Recombinant Protein

UniProt No. :

P47741

Internal Search Terms :

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more info or order :

NKMAX product webpage