Recombinant Mouse Erythropoietin/EPO Protein | NKMAX ATGP3959 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant Mouse Erythropoietin/EPO Protein

catalog :

ATGP3959

quantity :

10 ug

price :

150 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant Mouse Erythropoietin/EPO Protein

Domain :

27-192aa

Catalog number (SKU) :

ATGP3959

NCBI :

NP_031968

Description :

EPO, also known as erythropoietin, is a glycoprotein hormone in the type I cytokine family and is related to thrombopoietin. It is primarily produced in the kidney by a population of fibroblast-like cortical interstitial cells adjacent to the proximal tubules. This protein can be found in the plasma and regulates red cell production by promoting erythroid differentiation and initiating hemoglobin synthesis. It also has neuroprotective activity against a variety of potential brain injuries and anti-apoptotic functions in several tissue types. Recombinant mouse EPO, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Alternative Names :

Erythropoietin, erythropoietin isoform 1 precursor, Epo

Concentration :

0.25mg/ml (determined by Absorbance at 280nm)

Formulation :

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Koury, M.J., et al. (2005) Exp. Hematol. 33:1263.;; Jelkmann W., et al. (2007) Eur J Haematol. 78:183-205.

Purity :

> 95% by SDS-PAGE

Bioactivity Comment Only :

Measured in a cell proliferation assay using TF-1 human erythroleukemic cells. The ED50 range ≤ 2ng/ml.

Applications :

SDS-PAGE, Bioactivity

Antigen Species :

Mouse

Gene Category :

Angiogenesis, Cardiovascular

Molecular Weight :

19.8kDa (176aa)

Endotoxin :

< 1 EU per 1ug of protein (determined by LAL method)

Bioactivity Comment and Pics :

Mouse EPO stimulates cell proliferation of the TF-1 human erythroleukemic cells. The ED50 range ≤ 2ng/ml.

Amino Acid Sequence :

MAPPRLI CDSRVLERYI LEAKEAENVT MGCAEGPRLS ENITVPDTKV NFYAWKRMEV EEQAIEVWQG LSLLSEAILQ AQALLANSSQ PPETLQLHID KAISGLRSLT SLLRVLGAQK ELMSPPDTTP PAPLRTLTVD TFCKLFRVYA NFLRGKLKLY TGEVCRRGDR

Tag :

His-Tag

Expression System :

Baculovirus

Predicted nterm :

Ala

Product Type Name :

Recombinant Protein

UniProt No. :

P07321

Internal Search Terms :

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more info or order :

NKMAX product webpage