protein

Recombinant human ICAM-5 protein

ATGP3957

10 ug

140 USD

Recombinant human ICAM-5 protein

23-835aa

ATGP3957

NP_003250

ICAM-5, also known as telencephalin, is a cell surface glycoprotein belonging to the immunoglobulin superfamily. Human ICAM-5 is expressed on the surface of telencephalic neurons and displays two types of adhesion activity, homophilic binding between neurons and heterophilic binding between neurons and leukocytes. The tissue of ICAM-5, being expressed only in telencephalic regions of the central nervous system. Like other ICAMs, ICAM-5 binds to the leukocyte integrin LFA-1. Recombinant human ICAM-5, fused to hIgG-His-tag at C-terminus, was expressed in HEK293 cell and purified by using conventional chromatography techniques.

Intercellular adhesion molecule 5, ICAM5, ICAM-5, Telencephalin, telencephalin, TLN, TLCN, TLNtelencephalin, TLCNTelencephalin

0.5mg/ml (determined by Bradford assay)

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Yoshihara, Y. et al. (1994) Neuron 12:541-553.;;Tain, L. et al. (2000) Eur. J. Immunol. 30:810-818.;;Mizuno, T. et al. (1997) J. Biol. Chem. 272:1156-1163.

> 90% by SDS-PAGE

SDS-PAGE

Human

Immunology, Adhesion & Movement, Neuroscience

113.8kDa (1052aa)

< 1 EU per 1ug of protein (determined by LAL method)

LFGLSAVSQE PFWADLQPRV AFVERGGSLW LNCSTNCPRP ERGGLETSLR RNGTQRGLRW LARQLVDIRE PETQPVCFFR CARRTLQARG LIRTFQRPDR VELMPLPPWQ PVGENFTLSC RVPGAGPRAS LTLTLLRGAQ ELIRRSFAGE PPRARGAVLT ATVLARREDH GANFSCRAEL DLRPHGLGLF ENSSAPRELR TFSLSPDAPR LAAPRLLEVG SERPVSCTLD GLFPASEARV YLALGDQNLS PDVTLEGDAF VATATATASA EQEGARQLVC NVTLGGENRE TRENVTIYSF PAPLLTLSEP SVSEGQMVTV TCAAGAQALV TLEGVPAAVP GQPAQLQLNA TENDDRRSFF CDATLDVDGE TLIKNRSAEL RVLYAPRLDD SDCPRSWTWP EGPEQTLRCE ARGNPEPSVH CARSDGGAVL ALGLLGPVTR ALSGTYRCKA ANDQGEAVKD VTLTVEYAPA LDSVGCPERI TWLEGTEASL SCVAHGVPPP DVICVRSGEL GAVIEGLLRV AREHAGTYRC EATNPRGSAA KNVAVTVEYG PRFEEPSCPS NWTWVEGSGR LFSCEVDGKP QPSVKCVGSG GATEGVLLPL APPDPSPRAP RIPRVLAPGI YVCNATNRHG SVAKTVVVSA ESPPEMDEST CPSHQTWLEG AEASALACAA RGRPSPGVRC SREGIPWPEQ QRVSREDAGT YHCVATNAHG TDSRTVTVGV EYRPVVAELA ASPPGGVRPG GNFTLTCRAE AWPPAQISWR APPGALNIGL SSNNSTLSVA GAMGSHGGEY ECAATNAHGR HARRITVRVA GPW

hIgG-His-Tag

HEK293

Leu23

Recombinant Protein

Q9UMF0

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