Recombinant canine IL-1 beta/IL1B protein | NKMAX ATGP3956 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant canine IL-1 beta/IL1B protein

catalog :

ATGP3956

quantity :

10 ug

price :

160 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant canine IL-1 beta/IL1B protein

Domain :

114-265aa

Catalog number (SKU) :

ATGP3956

NCBI :

NP_001033060.1

Description :

Interleukin-1 (IL-1) has been considered a potentially important inflammatory mediator. It is composed of two distinct proteins, called as IL-1alpha and IL-1beta. IL-1beta is a proinflammatory cytokine produced in a variety of cells including monocytes, tissue macrophages, keratinocytes and other epithelial cells. Both IL-1alpha and IL-1beta bind to the same receptor and they are structurally related polypeptides that share approximately 20% amino acid. Recombinant canine IL-1beta was expressed in E. coli and purified by using conventional chromatography techniques.

Alternative Names :

Interleukin-1 beta, IL-1 beta

Concentration :

1mg/ml (determined by absorbance at 280nm)

Formulation :

Liquid in. Phosphate-Buffered Saline (pH 7.4)

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Allan SM., et al. (2005), Nat. Rev. Immunol. 5:629;; Curr Pharm Des. (2017), 23(32):4893-4905.;;

Purity :

> 95% by SDS-PAGE

Bioactivity Comment Only :

Measured in a cell proliferation assay using D10.G4.1 mouse helper T cells. The ED50 range ≤ 5pg/ml.

Applications :

SDS-PAGE, Bioactivity

Antigen Species :

Canine

Gene Category :

Hormones & Cytokines

Molecular Weight :

17.5 kDa (153aa) confirmed by MALDI-TOF

Endotoxin :

< 1 EU per 1ug of protein (determined by LAL method)

Bioactivity Comment and Pics :

Canine IL-1B stimulates cell proliferation of the D10.G4.1 mouse helper T cells. The ED50 range range ≤ 5pg/ml.

Amino Acid Sequence :

MAAMQSVDCK LQDISHKYLV LSNSYELRAL HLNGENVNKQ VVFHMSFVHG DESNNKIPVV LGIKQKNLYL SCVMKDGKPT LQLEKVDPKV YPKRKMEKRF VFNKIEIKNT VEFESSQYPN WYISTSQVEG MPVFLGNTRG GQDITDFTME FSS

Tag :

Non-Tagged

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

Q2VCE2

Internal Search Terms :

beta proprotein, Catabolin, IL 1, IL 1 b, IL 1b, IL 1beta, IL 1 beta, IL1, IL-1, IL1 b, IL1 beta, IL1b, IL-1b, IL1-beta, IL-1beta, IL-1-beta, IL1F2, Interleukin 1, Interleukin 1 b, Interleukin 1 beta, Interleukin 1b, Interleukin 1beta, ATGP3956-10ug, ATGP3956-20ug, ATGP3956-50ug, ATGP3956-100ug, ATGP3956-250ug, ATGP3956-500ug, ATGP3956-1mg, ATGP3956-010, ATGP3956-020, ATGP3956-050, ATGP3956-100, ATGP3956-250, ATGP3956-500, ATGP3956-01M

more info or order :

NKMAX product webpage