Recombinant mouse CD30/TNFRSF8 protein | NKMAX ATGP3949 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant mouse CD30/TNFRSF8 protein

catalog :

ATGP3949

quantity :

10 ug

price :

90 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant mouse CD30/TNFRSF8 protein

Domain :

19-258aa

Catalog number (SKU) :

ATGP3949

NCBI :

NP_033427

Description :

CD30/TNFRSF8, also known as TNF Receptor Superfamily Member 8, is a member of TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. CD30 contributes to thymic negative selection by inducing the apoptotic cell death of CD4+CD8+ T cells. In B cells, CD30 ligation promotes cellular proliferation and antibody production in addition to the expression of CXCR4, CCL3, and CCL5. Recombinant mouse CD30/TNFRSF8 protein, fused to hIgG-His tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Alternative Names :

Tumor necrosis factor receptor superfamily member 8, CD30L receptor, Lymphocyte activation antigen CD30, CD_antigen, CD30, Ki-1, D1S166E, ki

Concentration :

1mg/ml (determined by Absorbance at 280nm)

Formulation :

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

So T, Ishii N. (2019) Adv Exp Med Biol. 1189:53-84.;;Jeon SH, et al, (2015) Acta Odontol Scand. 73(8):588-594.

Purity :

> 90% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Mouse

Gene Category :

Immunology

Molecular Weight :

52.2kDa (479aa)

Endotoxin :

< 1 EU per 1ug of protein (determined by LAL method)

Amino Acid Sequence :

FPTDRPLKTT CAGDLSHYPG EAARNCCYQC PSGLSPTQPC PRGPAHCRKQ CAPDYYVNED GKCTACVTCL PGLVEKAPCS GNSPRICECQ PGMHCCTPAV NSCARCKLHC SGEEVVKSPG TAKKDTICEL PSSGSGPNCS NPGDRKTLTS HATPQAMPTL ESPANDSARS LLPMRVTNLV QEDATELVKV PESSSSKARE PSPDPGNAEK NMTLELPSPG TLPDISTSEN SKEPASTAST

Tag :

hIgG-His-Tag

Expression System :

Baculovirus

Predicted nterm :

Phe 19

Product Type Name :

Recombinant Protein

UniProt No. :

Q60846

Internal Search Terms :

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more info or order :

NKMAX product webpage