product summary
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company name :
NKMAX
product type :
protein
product name :
Recombinant mouse SPARC protein
catalog :
ATGP3945
quantity :
10 ug
price :
70 USD
more info or order :
product information
Product Type :
Proteins
Item Name :
Recombinant mouse SPARC protein
Domain :
18-302aa
Catalog number (SKU) :
ATGP3945
NCBI :
NP_033268
Description :
SPARC, also known as osteonectin and BM40, is a secreted matricellular glycoprotein that belongs to a group of functionally related glycoproteins that includes tenascins C and X, thrombospondins 1 and 2, and osteopontin. It is a major bone-related protein that is also present in nonmineralized tissues and in platelets and is matricellular molecule regulating interactions between cells and their surrounding extracellular matrix (ECM). This protein is produced by fibroblasts, capillary endothelial cells, platelets and macrophages, especially in areas of tissue morphogenesis and remodeling. It shows context-specific effects, but generally inhibits adhesion, spreading and proliferation, and promotes collagen matrix formation. It is abundantly expressed in bone, where it promotes osteoblast differentiation and inhibits adipogenesis. Recombinant mouse SPARC, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Alternative Names :
Basement-membrane protein 40, BM-40,Osteonectin, ON, Secreted protein acidic and rich in cysteine, Sparc
Concentration :
0.25mg/ml (determined by Absorbance at 280nm)
Formulation :
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Mizuho Fukunaga-Kalabi., et al, (2008) Cancer Microenviron. 1:93-102.;; Katarina Kos., et al, (2010) Nat Rev Endocrinol. 6:225-235.;; Sharon L I Wong., et al, (2017) Br J Pharmacol. 174:3-14.
Purity :
> 95% by SDS-PAGE
Applications :
SDS-PAGE
Antigen Species :
Mouse
Gene Category :
Cell Cycle
Molecular Weight :
33.3kDa (291aa)
Endotoxin :
<1 EU per 1ug of protein (determined by LAL method)
Amino Acid Sequence :
APQQTEVAEE IVEEETVVEE TGVPVGANPV QVEMGEFEDG AEETVEEVVA DNPCQNHHCK HGKVCELDES NTPMCVCQDP TSCPAPIGEF EKVCSNDNKT FDSSCHFFAT KCTLEGTKKG HKLHLDYIGP CKYIAPCLDS ELTEFPLRMR DWLKNVLVTL YERDEGNNLL TEKQKLRVKK IHENEKRLEA GDHPVELLAR DFEKNYNMYI FPVHWQFGQL DQHPIDGYLS HTELAPLRAP LIPMEHCTTR FFETCDLDND KYIALEEWAG CFGIKEQDIN KDLVI
Tag :
His-Tag
Expression System :
Baculovirus
Predicted nterm :
Ala
Product Type Name :
Recombinant Protein
UniProt No. :
P07214
Internal Search Terms :
,ATGP3945-10ug,ATGP3945-20ug,ATGP3945-50ug,ATGP3945-100ug,ATGP3945-250ug,ATGP3945-500ug,ATGP3945-1mg,ATGP3945-10,ATGP3945-20,ATGP3945-50,ATGP3945-100,ATGP3945-250,ATGP3945-500,ATGP3945-1
more info or order :
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.