product summary
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company name :
NKMAX
product type :
protein
product name :
Recombinant human GDNF protein
catalog :
ATGP3942
quantity :
10 ug
price :
160 USD
more info or order :
product information
Product Type :
Proteins
Item Name :
Recombinant human GDNF protein
Domain :
109-211aa
Catalog number (SKU) :
ATGP3942
NCBI :
NP_000505.1
Description :
GDNF, also known as Glial cell-derived neurotrophic factor, is a member of the GDNF family of ligands (GFL). This Protein has been found that GFLs play a role in a number of biological processes including cell survival, neurite outgrowth, cell differentiation and cell migration. It promotes the survival of many types of neurons and signals through GFRa receptors, particularly GFRa1. These neuronal populations die in the course of Parkinson's disease and amyotrophic lateral sclerosis (ALS). GDNF also regulates kidney development and spermatogenesis, and has a powerful and rapid negative (ameliorating) effect on alcohol consumption. Recombinant human GDNF, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Alternative Names :
Glial cell line-derived neurotrophic factor, hGDNF, Astrocyte-derived trophic factor, ATF, ATF1, ATF2, HFB1-GDNF, HSCR3
Concentration :
0.25mg/ml (determined by Absorbance at 280nm)
Formulation :
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol.
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Lin LF., et al, (1993) Science. 260:1130–1132.;; Carnicella S., et al, (2008) United States of America. 105: 8114–8119.
Purity :
> 90% by SDS-PAGE
Bioactivity Comment Only :
Measured by its binding ability in a functional ELISA with Human GFR alpha-1 (CAT# ATGP4154).
Applications :
SDS-PAGE, Bioactivity
Antigen Species :
Human
Gene Category :
Immunology
Molecular Weight :
12.8kDa (113aa)
Endotoxin :
< 1 EU per 1ug of protein (determined by LAL method)
Bioactivity Comment and Pics :
Human GDNF is coated at 0.5 ug/ml (100 ul/well) can bind Human GFR alpha-1 (CAT# ATGP4154) in a Functional ELISA assay.
Amino Acid Sequence :
RGQRGK NRGCVLTAIH LNVTDLGLGY ETKEELIFRY CSGSCDAAET TYDKILKNLS RNRRLVSDKV GQACCRPIAF DDDLSFLDDN LVYHILRKHS AKRCGCI
Tag :
His-Tag
Expression System :
Baculovirus
Predicted nterm :
Ala
Product Type Name :
Recombinant Protein
UniProt No. :
P39905
Internal Search Terms :
,ATGP3942-10ug,ATGP3942-20ug,ATGP3942-50ug,ATGP3942-100ug,ATGP3942-250ug,ATGP3942-500ug,ATGP3942-1mg,ATGP3942-10,ATGP3942-20,ATGP3942-50,ATGP3942-100,ATGP3942-250,ATGP3942-500,ATGP3942-1
more info or order :
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.