Recombinant human ABP1/AOC1 protein | NKMAX ATGP3938 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human ABP1/AOC1 protein

catalog :

ATGP3938

quantity :

10 ug

price :

140 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human ABP1/AOC1 protein

Domain :

20-751aa

Catalog number (SKU) :

ATGP3938

NCBI :

NP_001082

Description :

ABP1, also known as diamine oxidase (DAO) and amine oxidase copper domain-containing protein 1 (AOC1), is a member of the copper-containing amine oxidase family. This enzyme catalyzes the oxidation of a wide range of biogenic amines including many neurotransmitters, histamine and xenobiotic amines. It has an important role in the catabolism of histamine and other bioactive polyamines. Deficiencies in ABP1 can result in histaminosis or dietary histamine intolerance. This protein is also contributed to Tumor Progression by Promoting the AKT and EMT Pathways in Gastric Cancer. Recombinant human AOC1, fused to His-tag at C-terminus, was expressed in HEK293 cell and purified by using conventional chromatography techniques.

Alternative Names :

Amiloride-sensitive amine oxidase, DAO, Diamine oxidase, Amiloride-binding protein 1, Amine oxidase copper domain-containing protein 1, Histaminase, Kidney amine oxidase, KAO, ABP, ABP1, DAO1

Concentration :

0.25mg/ml (determined by absorbance at 280nm)

Formulation :

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Novotny, W.F. et al. (1994) J. Biol. Chem. 269:9921-9925.;; Jones, B.L. and G.L. Kearns (2011) Clin. Pharmacol. Ther. 89:189-197.;; Bieganski, T. et al. (1983) Biochim. Biophys. Acta 756:196-203.;;

Purity :

> 90% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Immunology

Molecular Weight :

84.2kDa (738aa)

Endotoxin :

< 1 EU per 1ug of protein (determined by LAL method)

Amino Acid Sequence :

EPSPGTLPRK AGVFSDLSNQ ELKAVHSFLW SKKELRLQPS STTTMAKNTV FLIEMLLPKK YHVLRFLDKG ERHPVREARA VIFFGDQEHP NVTEFAVGPL PGPCYMRALS PRPGYQSSWA SRPISTAEYA LLYHTLQEAT KPLHQFFLNT TGFSFQDCHD RCLAFTDVAP RGVASGQRRS WLIIQRYVEG YFLHPTGLEL LVDHGSTDAG HWAVEQVWYN GKFYGSPEEL ARKYADGEVD VVVLEDPLPG GKGHDSTEEP PLFSSHKPRG DFPSPIHVSG PRLVQPHGPR FRLEGNAVLY GGWSFAFRLR SSSGLQVLNV HFGGERIAYE VSVQEAVALY GGHTPAGMQT KYLDVGWGLG SVTHELAPGI DCPETATFLD TFHYYDADDP VHYPRALCLF EMPTGVPLRR HFNSNFKGGF NFYAGLKGQV LVLRTTSTVY NYDYIWDFIF YPNGVMEAKM HATGYVHATF YTPEGLRHGT RLHTHLIGNI HTHLVHYRVD LDVAGTKNSF QTLQMKLENI TNPWSPRHRV VQPTLEQTQY SWERQAAFRF KRKLPKYLLF TSPQENPWGH KRTYRLQIHS MADQVLPPGW QEEQAITWAR YPLAVTKYRE SELCSSSIYH QNDPWHPPVV FEQFLHNNEN IENEDLVAWV TVGFLHIPHS EDIPNTATPG NSVGFLLRPF NFFPEDPSLA SRDTVIVWPR DNGPNYVQRW IPEDRDCSMP PPFSYNGTYR PV

Tag :

His-Tag

Expression System :

HEK293

Predicted nterm :

Glu19

Product Type Name :

Recombinant Protein

UniProt No. :

P19801

Internal Search Terms :

,ATGP3938-10ug,ATGP3938-20ug,ATGP3938-50ug,ATGP3938-100ug,ATGP3938-250ug,ATGP3938-500ug,ATGP3938-1mg,ATGP3938-10,ATGP3938-20,ATGP3938-50,ATGP3938-100,ATGP3938-250,ATGP3938-500,ATGP3938-1

more info or order :

NKMAX product webpage