product summary
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company name :
NKMAX
product type :
protein
product name :
Recombinant Porcine GM-CSF protein
catalog :
ATGP3935
quantity :
10 ug
price :
160 USD
more info or order :
product information
Product Type :
Proteins
Item Name :
Recombinant Porcine GM-CSF protein
Domain :
18-144aa
Catalog number (SKU) :
ATGP3935
NCBI :
NP_999283
Description :
GM-CSF, also known as granulocyte macrophage colony-stimulating factor, is a hematopoietic growth factor that stimulates the development of neutrophils and macrophages and promotes the proliferation and development of early erythroid megakaryocytic and eosinophilic progenitor cells. It is produced in by endothelial cells, monocytes, fibroblasts and T-lymphocytes. GM-CSF inhibits neutrophil migration and enhances the functional activity of the mature end-cells. Recombinant porcine GM-CSF was expressed in E. coli and purified by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer.
Alternative Names :
Colony stimulating factor, Colony Stimulating Factor 2, Colony stimulating factor 2 (granulocyte-macrophage), Colony-stimulating factor, CSF, CSF 2, CSF2, CSF2_HUMAN, GM-CSF, GMCSF
Concentration :
0.5mg/ml (determined by absorbance at 280nm)
Formulation :
Liquid. In Phosphate-Buffered Saline (pH7.4)
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Trapnell BC, et al. (2002) Annu Rev Physiol. 64, 775-80. Wong GG, et al (1985) Science, 228, 810-815.
Purity :
> 95% by SDS - PAGE
Bioactivity Comment Only :
Measured in a cell proliferation assay using TF-1 human erythroleukemic cells. The ED50 range ≤ 40 ng/ml.
Applications :
SDS-PAGE, Bioactivity
Antigen Species :
Pocrine
Gene Category :
Growth factors
Molecular Weight :
16.6 kDa (148aa), confirmed by MALDI-TOF
Endotoxin :
< 1 EU per 1ug of protein (determined by LAL method)
Bioactivity Comment and Pics :
Porcine GM-CSF stimulates cell proliferation of the TF-1 human erythroleukemic cells. The ED50 range ≤ 40 ng/ml.
Amino Acid Sequence :
APTRPPSPV TRPWQHVDAI KEALSLLNNS NDTAAVMNET VDVVCEMFDP QEPTCVQTRL NLYKQGLRGS LTRLKSPLTL LAKHYEQHCP LTEETSCETQ SITFKSFKDS LNKFLFTIPF DCWGPVKK
Tag :
His-Tag
Expression System :
E.coli
Product Type Name :
Recombinant Protein
UniProt No. :
Q29118
Internal Search Terms :
Granulocyte Macrophage Colony Stimulating Factor, Granulocyte-macrophage colony-stimulating factor, MGC131935, MGC138897, MGI1GM, Molgramostin, Pluripoietin-a, Sargramostim,ATGP3935-10ug,ATGP3935-20ug,ATGP3935-50ug,ATGP3935-100ug,ATGP3935-250ug,ATGP3935-500ug,ATGP3935-1mg,ATGP3935-10,ATGP3935-20,ATGP3935-50,ATGP3935-100,ATGP3935-250,ATGP3935-500,ATGP3935-1
more info or order :
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.