Recombinant mouse IL-1 alpha/IL1A protein | NKMAX ATGP3932 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant mouse IL-1 alpha/IL1A protein

catalog :

ATGP3932

quantity :

10 ug

price :

160 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant mouse IL-1 alpha/IL1A protein

Domain :

115-270aa

Catalog number (SKU) :

ATGP3932

NCBI :

NP_034684

Description :

IL-1 alpha /IL-1F1, also known as interleukin-1 alpha, is a member of the interleukin-1 cytokine family. Cytokines are protein signaling compounds that are the main mediators of the immune response. This protein is produced mainly by activated macrophages, as well as neutrophils, epithelial cells, and endothelial cells. It possesses metabolic, physiological, haematopoietic activities, and plays one of the central roles in the regulation of the immune responses. It binds to the interleukin-1 receptor. It is on the pathway that activates tumor necrosis factor-alpha. Also, it stimulates thymocyte proliferation by inducing IL-2 release, B cell maturation and proliferation. Recombinant mouse IL-1 alpha, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Alternative Names :

Interleukin-1 alpha precursor, Interleukin 1 alpha, IL-1F1, IL-1A, IL-1 alpha

Concentration :

0.5mg/ml (determined by Absorbance at 280nm)

Formulation :

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Dinarello CA., et al. (1997) Semin Oncol. 24:S9-81-S9-93.;; Bankers-Fulbright JL., et al. (1996) Life Sci. 59:61-83.

Purity :

> 90% by SDS-PAGE

Bioactivity Comment Only :

Measured in a cell proliferation assay using D10.G4.1 mouse helper T cells. The ED50 range ≤ 0.15 ng/ml.

Applications :

SDS-PAGE, Bioactivity

Antigen Species :

Mouse

Gene Category :

Immunology

Molecular Weight :

19.0kDa (165aa)

Endotoxin :

< 1 EU per 1ug of protein (determined by LAL method)

Bioactivity Comment and Pics :

Mouse IL-1 alpha /IL-1F1 stimulates cell proliferation of the D10.G4.1 mouse helper T cells. The ED50 range ≤ 0.15 ng/ml.

Amino Acid Sequence :

SAPYTYQ SDLRYKLMKL VRQKFVMNDS LNQTIYQDVD KHYLSTTWLN DLQQEVKFDM YAYSSGGDDS KYPVTLKISD SQLFVSAQGE DQPVLLKELP ETPKLITGSE TDLIFFWKSI NSKNYFTSAA YPELFIATKE QSRVHLARGL PSMTDFQIS

Tag :

His-Tag

Expression System :

Baculovirus

Predicted nterm :

Ala

Product Type Name :

Recombinant Protein

UniProt No. :

P01582

Internal Search Terms :

ATGP3778, Pro-interleukin-1-alpha, Pro interleukin 1 alpha, Preinterleukin 1 alpha, Interleukin-1 alpha precursor, Interleukin 1 alpha, IL1F1, IL-1a, IL1a, IL-1 alpha, IL1 alpha, IL-1 a, IL1 a, IL 1 alpha, IL 1 a, Hematopoietin-1, Hematopoietin1, Hematopoietin 1, ATGP3932-10ug, ATGP3932-20ug, ATGP3932-50ug, ATGP3932-100ug, ATGP3932-250ug, ATGP3932-500ug, ATGP3932-1mg, ATGP3932-010, ATGP3932-020, ATGP3932-050, ATGP3932-100, ATGP3932-250, ATGP3932-500, ATGP3932-01M, ATGP3778

more info or order :

NKMAX product webpage