product summary
Loading...
company name :
NKMAX
product type :
protein
product name :
Recombinant mouse Thrombopoietin protein
catalog :
ATGP3930
quantity :
10 ug
price :
140 USD
more info or order :
product information
Product Type :
Proteins
Item Name :
Recombinant mouse Thrombopoietin protein
Domain :
22-356aa
Catalog number (SKU) :
ATGP3930
NCBI :
NP_033405
Description :
Thrombopoietin(THPO), also known as megakaryocyte growth and development factor (MGDF), is a glycoprotein hormone produced by the liver and kidney which regulates the production of platelets. It stimulates the production and differentiation of megakaryocytes, the bone marrow cells that bud off large numbers of platelets. Megakaryocytopoiesis is the cellular development process that leads to platelet production. It is a humoral growth factor necessary for megakaryocyte proliferation and maturation, as well as for thrombopoiesis. This protein is the ligand for MLP/C_MPL, the product of myeloproliferative leukemia virus oncogene. Recombinant mouse Thrombopoietin, fused to His-tag at C-terminus, was expressed in HEK293 cell and purified by using conventional chromatography techniques.
Alternative Names :
Thpo, C-mpl ligand,ML, Megakaryocyte colony-stimulating factor, Megakaryocyte growth and development factor, MGDF, Myeloproliferative leukemia virus oncogene ligand, Mgdf, Ml, Mpllg, Tpo, thrombopoietin isoform 1
Concentration :
0.5mg/ml (determined by absorbance at 280nm)
Formulation :
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Jenkins JM., et al. (2007) Blood. 109:4739-4741.;; Hitchcock IS., et al. (2014) Br J Haemato. 165:259-268.
Purity :
> 90% by SDS-PAGE
Bioactivity Comment Only :
Measured in a cell proliferation assay using MO7e human megakaryocytic leukemic cells. The ED50 range ≤4ng/ml.
Applications :
SDS-PAGE, Bioactivity
Antigen Species :
Mouse
Gene Category :
Cardiovascular
Molecular Weight :
36.4 kDa (341aa)
Endotoxin :
< 1 EU per 1ug of protein (determined by LAL method)
Bioactivity Comment and Pics :
Mouse Thrombopoietin stimulates cell proliferation of the MO7e human megakaryocytic leukemic cells. The ED50 range ≤4 ng/ml.
Amino Acid Sequence :
SPVAPACDPR LLNKLLRDSH LLHSRLSQCP DVDPLSIPVL LPAVDFSLGE WKTQTEQSKA QDILGAVSLL LEGVMAARGQ LEPSCLSSLL GQLSGQVRLL LGALQGLLGT QLPLQGRTTA HKDPNALFLS LQQLLRGKVR FLLLVEGPTL CVRRTLPTTA VPSSTSQLLT LNKFPNRTSG LLETNFSVTA RTAGPGLLSR LQGFRVKITP GQLNQTSRSP VQISGYLNRT HGPVNGTHGL FAGTSLQTLE ASDISPGAFN KGSLAFNLQG GLPPSPSLAP DGHTPFPPSP ALPTTHGSPP QLHPLFPDPS TTMPNSTAPH PVTMYPHPRN LSQET
Tag :
His-Tag
Expression System :
HEK293
Predicted nterm :
Ser22
Product Type Name :
Recombinant Protein
UniProt No. :
P40226
Internal Search Terms :
Thrombopoietin,ATGP3930-10ug,ATGP3930-20ug,ATGP3930-50ug,ATGP3930-100ug,ATGP3930-250ug,ATGP3930-500ug,ATGP3930-1mg,ATGP3930-10,ATGP3930-20,ATGP3930-50,ATGP3930-100,ATGP3930-250,ATGP3930-500,ATGP3930-1
more info or order :
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.