Recombinant mouse Aminopeptidase N/CD13 protein | NKMAX ATGP3925 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant mouse Aminopeptidase N/CD13 protein

catalog :

ATGP3925

quantity :

10 ug

price :

150 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant mouse Aminopeptidase N/CD13 protein

Domain :

33-966aa

Catalog number (SKU) :

ATGP3925

NCBI :

NP_032512

Description :

Anpep, also known as aminopeptidase N, is located in the small-intestinal and renal microvillar membrane, and also in other plasma membranes. It plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. This protein is also involved in the processing of various peptides including peptide hormones, such as angiotensin III and IV, neuropeptides, and chemokines. It has a role in angiogenesis and promote cholesterol crystallization and in amino acid transport by acting as binding partner of amino acid transporter SLC6A19 and regulating its activity. Recombinant mouse Anpep, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Alternative Names :

Anpep, AP-M, AP-N, Apn, Cd13, P150, mAPN, Alanyl aminopeptidase, Aminopeptidase M, Membrane protein p161, Microsomal aminopeptidase, CD13, Lap-1, Lap1, aminopeptidase N

Concentration :

0.5mg/ml (determined by absorbance at 280nm)

Formulation :

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Azimi A., et al. (2017) Cell Death Dis. 8:e3029.;; S첩rensen KD., et al. (2013) Br J Cancer. 108:420-428.

Purity :

> 95% by SDS-PAGE

Bioactivity Comment Only :

Specific activity is > 4,000pmol/min/ug, and is defined as the amount of enzyme that hydrolyze 1pmole of H-Ala-AMC to Alanine and AMC per minute at pH7.5 at 25C.

Applications :

SDS-PAGE,Enzyme Activity

Antigen Species :

Mouse

Gene Category :

Immunology

Molecular Weight :

107.5 kDa (943aa)

Endotoxin :

< 1 EU per 1ug of protein (determined by LAL method)

Bioactivity Comment and Pics :

Specific activity is > 4,000 pmol/min/ug, and is defined as the amount of enzyme that hydrolyze 1pmole of H-Ala-AMC to Alanine and AMC per minute at pH7.5 at 25C.

Amino Acid Sequence :

YAQEKNR NAENSATAPT LPGSTSATTA TTTPAVDESK PWNQYRLPKT LIPDSYRVIL RPYLTPNNQG LYIFQGNSTV RFTCNQTTDV IIIHSKKLNY TLKGNHRVVL RTLDGTPAPN IDKTELVERT EYLVVHLQGS LVEGRQYEMD SQFQGELADD LAGFYRSEYM EGDVKKVVAT TQMQAADARK SFPCFDEPAM KAMFNITLIY PNNLIALSNM LPKESKPYPE DPSCTMTEFH STPKMSTYLL AYIVSEFKNI SSVSANGVQI GIWARPSAID EGQGDYALNV TGPILNFFAQ HYNTSYPLPK SDQIALPDFN AGAMENWGLV TYRESSLVFD SQSSSISNKE RVVTVIAHEL AHQWFGNLVT VAWWNDLWLN EGFASYVEYL GADYAEPTWN LKDLMVLNDV YRVMAVDALA SSHPLSSPAD EIKTPDQIME LFDSITYSKG ASVIRMLSSF LTEDLFKKGL SSYLHTYQYS NTVYLDLWEH LQKAVNQQTA VQPPATVRTI MDRWILQMGF PVITVNTNTG EISQKHFLLD SKSNVTRPSE FNYIWIAPIP FLKSGQEDHY WLDVEKNQSA KFQTSSNEWI LLNINVTGYY LVNYDENNWK KLQNQLQTDL SVIPVINRAQ IIHDSFNLAS AKMIPITLAL DNTLFLVKEA EYMPWQAALS SLNYFTLMFD RSEVYGPMKR YLKKQVTPLF FYFQNRTNNW VNRPPTLMEQ YNEINAISTA CSSGLKECRD LVVELYSQWM KNPNNNTIHP NLRSTVYCNA IAFGGEEEWN FAWEQFRNAT LVNEADKLRS ALACSKDVWI LNRYLSYTLN PDYIRKQDTT STIISIASNV AGHPLVWDFV RSNWKKLFEN YGGGSFSFAN LIQGVTRRFS SEFELQQLEQ FKADNSATGF GTGTRALEQA LEKTRANIDW VKENKDAVFK WFTENSS

Tag :

His-Tag

Expression System :

Baculovirus

Predicted nterm :

Ala

Product Type Name :

Recombinant Protein

UniProt No. :

P97449

Internal Search Terms :

Aminopeptidase N, CD13,ATGP3925-10ug,ATGP3925-20ug,ATGP3925-50ug,ATGP3925-100ug,ATGP3925-250ug,ATGP3925-500ug,ATGP3925-1mg,ATGP3925-10,ATGP3925-20,ATGP3925-50,ATGP3925-100,ATGP3925-250,ATGP3925-500,ATGP3925-1

more info or order :

NKMAX product webpage