product summary
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company name :
NKMAX
product type :
protein
product name :
Recombinant mouse HVEM/TNFRSF14 protein
catalog :
ATGP3916
quantity :
10 ug
price :
87 USD
more info or order :
product information
Product Type :
Proteins
Item Name :
Recombinant mouse HVEM/TNFRSF14 protein
Domain :
39-206aa
Catalog number (SKU) :
ATGP3916
NCBI :
NP_849262.1
Description :
HVEM/TNFRSF14, also known as tumor necrosis factor receptor superfamily member 14, is a member of TNF receptor superfamily. This protein was originally known as herpesvirus entry mediator A (HveA); HveB and HveC are structurally unrelated proteins of the immunoglobulin superfamily. The cytoplasmic region of this receptor was found to bind to several TNF receptor associated factor (TRAF) family members, which may mediate the signal transduction pathways that activate the immune response. It promotes and inhibits T cell activity. This protein signals via the TRAF2-TRAF3 E3 ligase pathway to promote immune cell survival and differentiation. It participates in cell to cell contact signaling between antigen presenting cells and lymphocytes. This protein downregulates CD28 costimulatory signaling, restricting memory and alloantigen-specific immune response. Recombinant mouse HVEM/TNFRSF14, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Alternative Names :
Tumor necrosis factor receptor superfamily member 14, Herpes virus entry mediator A, Herpesvirus entry mediator A, HveA, Tumor necrosis factor receptor-like 2, TR2, CD270, HVEM, ATAR, LIGHTR
Concentration :
0.25mg/ml (determined by absorbance at 280nm)
Formulation :
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Choi EK., et al. (2013) J Endocrinol. 220:25-33.;; Kotsiou E., et al. (2018) Blood. 128:72-81.
Purity :
> 90% by SDS-PAGE
Applications :
SDS-PAGE
Antigen Species :
Mouse
Gene Category :
Immunology
Molecular Weight :
45.3 kDa (407aa)
Endotoxin :
< 1 EU per 1ug of protein (determined by LAL method)
Amino Acid Sequence :
QPSCRQEEFL VGDECCPMCN PGYHVKQVCS EHTGTVCAPC PPQTYTAHAN GLSKCLPCGV CDPDMGLLTW QECSSWKDTV CRCIPGYFCE NQDGSHCSTC LQHTTCPPGQ RVEKRGTHDQ DTVCADCLTG TFSLGGTQEE CLPWTNCSAF QQEVRRGTNS TDTTCSSQ
Tag :
hIgG-His-Tag
Expression System :
Baculovirus
Predicted nterm :
Gln39
Product Type Name :
Recombinant Protein
UniProt No. :
Q80WM9
Internal Search Terms :
HVEM, TNFRSF14,ATGP3916-10ug,ATGP3916-20ug,ATGP3916-50ug,ATGP3916-100ug,ATGP3916-250ug,ATGP3916-500ug,ATGP3916-1mg,ATGP3916-10,ATGP3916-20,ATGP3916-50,ATGP3916-100,ATGP3916-250,ATGP3916-500,ATGP3916-1
more info or order :
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.