Recombinant mouse Tyro3/Dtk protein | NKMAX ATGP3911 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant mouse Tyro3/Dtk protein

catalog :

ATGP3911

quantity :

10 ug

price :

80 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant mouse Tyro3/Dtk protein

Domain :

31-419aa

Catalog number (SKU) :

ATGP3911

NCBI :

NP_062265

Description :

Tyro3, also known as tyrosine-protein kinase receptor TYRO3 isoform A, is one of the receptor tyrosinekinase subfamily. It transduces signals from the extracellular matrix into the cytoplasm by binding to severalligands including TULP1 or GAS6. This protein regulates many physiological processes including cellsurvival, migration and differentiation. It activates the AKT survival pathway, including nuclear translocation of NF-kappa-B and up-regulation of transcription of NF-kappa-B-regulated genes. This protein plays a role invarious processes such as neuron protection from excitotoxic injury, platelet aggregation and cytoskeletonreorganization. Recombinant mouse Tyro3, fused to hIgG-His-tag at C-terminus, was expressed in insect celland purified by using conventional chromatography techniques.

Alternative Names :

Tyro3, AI323366, Brt, Dtk, Etk-2, etk2/tyro3, Rse, Sky, Tif, tk19-1, Tyrosine-protein kinasereceptor TYRO3, Etk2/tyro3, Tyrosine-protein kinase DTK, Tyrosine-protein kinase RSE,Tyrosine-protein kinase TIF

Concentration :

0.25mg/ml (determined by absorbance at 280nm)

Formulation :

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Shao H., et al. (2017) Biochem Biophys Res Commun. 490:1074-1079.;;Blades F., et al. (2018) Glia. 66:2209-2220.

Purity :

> 95% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Mouse

Gene Category :

Neuroscience

Molecular Weight :

68.9 kDa (628aa)

Endotoxin :

< 1 EU per 1ug of protein (determined by LAL method)

Amino Acid Sequence :

AGLKLMGAPV KMTVSQGQPV KLNCSVEGME DPDIHWMKDG TVVQNASQVS ISISEHSWIG LLSLKSVERS DAGLYWCQVK DGEETKISQS VWLTVEGVPF FTVEPKDLAV PPNAPFQLSC EAVGPPEPVT IYWWRGLTKV GGPAPSPSVL NVTGVTQRTE FSCEARNIKG LATSRPAIVR LQAPPAAPFN TTVTTISSYN ASVAWVPGAD GLALLHSCTV QVAHAPGEWE ALAVVVPVPP FTCLLRNLAP ATNYSLRVRC ANALGPSPYG DWVPFQTKGL APARAPQNFH AIRTDSGLIL EWEEVIPEDP GEGPLGPYKL SWVQENGTQD ELMVEGTRAN LTDWDPQKDL ILRVCASNAI GDGPWSQPLV VSSHDHAGRQ GPPHSRTSW

Tag :

hIgG-His-Tag

Expression System :

Baculovirus

Predicted nterm :

Ala31

Product Type Name :

Recombinant Protein

UniProt No. :

P55144

Internal Search Terms :

Tyro3, Dtk,ATGP3911-10ug,ATGP3911-20ug,ATGP3911-50ug,ATGP3911-100ug,ATGP3911-250ug,ATGP3911-500ug,ATGP3911-1mg,ATGP3911-10,ATGP3911-20,ATGP3911-50,ATGP3911-100,ATGP3911-250,ATGP3911-500,ATGP3911-1

more info or order :

NKMAX product webpage