product summary
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company name :
NKMAX
product type :
protein
product name :
Recombinant mouse Asparagine Synthetase/ASNS protein
catalog :
ATGP3908
quantity :
10 ug
price :
140 USD
more info or order :
product information
Product Type :
Proteins
Item Name :
Recombinant mouse Asparagine Synthetase/ASNS protein
Domain :
1-561aa
Catalog number (SKU) :
ATGP3908
NCBI :
NP_036185
Description :
ASNS, also known as Asparagine synthetase, is a one of cytoplasmic enzyme that generates asparagine from aspartate. It mainly distributes in mammalian organs, but basal expression is low in tissues other than the exocrine pancreas. This protein plays a role of cell growth, and its mRNA content is linked to changes in the cell cycle. Its mRNA is upregulated in response to the asparagine depletion, some of the toxic effects of themedication on normal cell activity. Above average presence of asparagine synthetase in certain leukemia strains has been linked to be a significant contributing factor of chemotherapy resistance, particularly to thechemotherapy drug, L-asparaginase. Also, it functions as potential biomarker for ovarian cancer, potential role in solid tumor metastasis. Recombinant mouse ASNS, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Alternative Names :
Asns, Asparagine synthetase, Glutamine-dependent asparagine synthetase
Concentration :
0.25mg/ml (determined by absorbance at 280nm)
Formulation :
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 40% glycerol
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Chan WK., et al. (2014) Blood. 123:3596-3606.;;Khater F., et al. (2017) Blood. 129:1729-1732.
Purity :
> 95% by SDS-PAGE
Applications :
SDS-PAGE
Antigen Species :
Mouse
Gene Category :
Metabolism
Molecular Weight :
65.1 kDa (567aa)
Endotoxin :
< 1 EU per 1ug of protein (determined by LAL method)
Amino Acid Sequence :
MCGIWALFGS DDCLSVQCLS AMKIAHRGPD AFRFENVNGY TNCCFGFHRL AVVDPLFGMQPIRVRKYPYL WLCYNGEIYN HKALQQRFEF EYQTNVDGEI ILHLYDKGGI EKTICMLDGVFAFILLDTAN KKVFLGRDTY GVRPLFKAMT EDGFLAVCSE AKGLVSLKHS TTPFLKVEPFLPGHYEVLDL KPNGKVASVE MVKYHHCTDE PLHAIYDSVE KLFPGFDLET VKNNLRILFDNAIKKRLMTD RRIGCLLSGG LDSSLVAASL LKQLKEAQVQ YPLQTFAIGM EDSPDLLAARKVANYIGSEH HEVLFNSEEG IQALDEVIFS LETYDITTVR ASVGMYLISK YIRKNTDSVVIFSGEGSDEL TQGYIYFHKA PSPEKAEEES ERLLKELYLF DVLRADRTTA AHGLELRVPFLDHRFSSYYL SLPPDMRIPK NGIEKHLLRE TFEDCNLLPK EILWRPKEAF SDGITSVKNSWFKILQDYVE HQVDDEMMSA SQKFPFNTP KTKEGYFYRQ IFERHYPGRA DWLTHYWMPK WINATDPSAR TLTHYKSAAK A
Tag :
His-Tag
Expression System :
Baculovirus
Predicted nterm :
Met1
Product Type Name :
Recombinant Protein
UniProt No. :
Q61024
Internal Search Terms :
Asparagine Synthetase, ASNS,ATGP3908-10ug,ATGP3908-20ug,ATGP3908-50ug,ATGP3908-100ug,ATGP3908-250ug,ATGP3908-500ug,ATGP3908-1mg,ATGP3908-10,ATGP3908-20,ATGP3908-50,ATGP3908-100,ATGP3908-250,ATGP3908-500,ATGP3908-1
more info or order :
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.