Recombinant mouse Mer protein | NKMAX ATGP3906 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant mouse Mer protein

catalog :

ATGP3906

quantity :

10 ug

price :

70 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant mouse Mer protein

Domain :

19-497aa

Catalog number (SKU) :

ATGP3906

NCBI :

NP_032613

Description :

Mer, also known as Tyrosine-protein kinase Mer, is one of the receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm. It regulates many physiological processes including cell survival, migration, differentiation, and phagocytosis of apoptotic cells. This protein plays a role in various processes such as macrophage clearance of apoptotic cells, platelet aggregation, cytoskeleton reorganization and engulfment. Mutations in this protein have been associated with disruption of the retinal pigment epithelium (RPE) phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa (RP). Recombinant mouse Mer, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Alternative Names :

Mertk, Proto-oncogene c-Mer, Receptor tyrosine kinase MerTK, Eyk, Mer, nmf12, Nyk,Tyrosine-protein kinase Mer

Concentration :

0.5mg/ml (determined by absorbance at 280nm)

Formulation :

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Grabiec AM., et al. (2018) Eur J Immunol. 48:855-860.;;McHenry CL., et al. (2004) Invest Ophthalmol Vis Sci. 45:1456-1463.

Purity :

> 95% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Mouse

Gene Category :

Neuroscience

Molecular Weight :

79.2 kDa (718aa)

Endotoxin :

< 1 EU per 1ug of protein (determined by LAL method)

Amino Acid Sequence :

GGTAEKWEET ELDQLFSGPL PGRLPVNHRP FSAPHSSRDQ LPPPQTGRSH PAHTAAPQVT STASKLLPPV AFNHTIGHIV LSEHKNVKFN CSINIPNTYQ ETAGISWWKD GKELLGAHHS ITQFYPDEEG VSIIALFSIA SVQRSDNGSY FCKMKVNNRE IVSDPIYVEV QGLPYFIKQP ESVNVTRNTA FNLTCQAVGP PEPVNIFWVQ NSSRVNEKPE RSPSVLTVPG LTETAVFSCE AHNDKGLTVS KGVHINIKVI PSPPTEVHIL NSTAHSILVS WVPGFDGYSP LQNCSIQVKE ADRLSNGSVM VFNTSASPHL YEIQQLQALA NYSIAVSCRN EIGWSAVSPW ILASTTEGAP SVAPLNITVF LNESNNILDI RWTKPPIKRQ DGELVGYRIS HVWESAGTYK ELSEEVSQNG SWAQIPVQIH NATCTVRIAA ITKGGIGPFS EPVNIIIPEH SKVDYAPSST PAPGNTDSM

Tag :

hIgG-His-Tag

Expression System :

Baculovirus

Predicted nterm :

Gly19

Product Type Name :

Recombinant Protein

UniProt No. :

Q60805

Internal Search Terms :

Mer,ATGP3906-10ug,ATGP3906-20ug,ATGP3906-50ug,ATGP3906-100ug,ATGP3906-250ug,ATGP3906-500ug,ATGP3906-1mg,ATGP3906-10,ATGP3906-20,ATGP3906-50,ATGP3906-100,ATGP3906-250,ATGP3906-500,ATGP3906-1

more info or order :

NKMAX product webpage