Recombinant mouse M-CSF protein | NKMAX ATGP3904 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant mouse M-CSF protein

catalog :

ATGP3904

quantity :

10 ug

price :

140 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant mouse M-CSF protein

Domain :

33-187aa

Catalog number (SKU) :

ATGP3904

NCBI :

NP_031804

Description :

M-CSF, also known as macrophage colony-stimulating factor 1 isoform 1, is one of the hematopoietic growth factors that regulate the growth and differentiation of blood cells. This protein is produced by monocytes,granulocytes, endothelial cells, and fibroblasts. It stimulates the formation of macrophage colonies, enhancesantibody-dependent, cell-mediated cytotoxicity by monocytes and macrophages, and inhibits bone resorption byosteoclasts. It plays an essential role in the regulation of survival, proliferation and differentiation ofhematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. This proteinpromotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and ininflammatory processes. Recombinant mouse M-CSF, fused to His-tag at C-terminus, was expressed in insect celland purified by using conventional chromatography techniques.

Alternative Names :

M-Csf, Macrophage colony-stimulating factor 1, CSF-1, MCSF, Csf1, C87615, MCSF, op, Processedmacrophage colony-stimulating factor 1

Concentration :

1mg/ml (determined by absorbance at 280nm)

Formulation :

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Richardsen E., et al. (2018) Anticancer Res. 35(2):865-874.;;Braza MS., et al. (2018) Am J Transplant. 18:1247-1255.

Purity :

> 90% by SDS-PAGE

Bioactivity Comment Only :

Measured in a cell proliferation assay using M-NFS-60 mouse myelogenous leukemia lymphoblast cells. The ED50 for this effect is ≤4ng/ml.

Applications :

SDS-PAGE, Bioactivity

Antigen Species :

Mouse

Gene Category :

Immunology

Molecular Weight :

19.1 kDa (164aa)

Endotoxin :

< 1 EU per 1ug of protein (determined by LAL method)

Bioactivity Comment and Pics :

Mouse M-CSF stimulates cell proliferation of the M-NFS-60 mouse myelogenous leukemia lymphoblast cells. The ED50 range is ≤4 ng/ml.

Amino Acid Sequence :

KEVSEHC SHMIGNGHLK VLQQLIDSQM ETSCQIAFEF VDQEQLDDPV CYLKKAFFLV QDIIDETMRF KDNTPNANAT ERLQELSNNL NSCFTKDYEE QNKACVRTFH ETPLQLLEKI KNFFNETKNL LEKDWNIFTK NCNNSFAKCS SRDVVTKP

Tag :

His-Tag

Expression System :

Baculovirus

Predicted nterm :

Ala

Product Type Name :

Recombinant Protein

UniProt No. :

P07141

Internal Search Terms :

M-CSF,ATGP3904-10ug,ATGP3904-20ug,ATGP3904-50ug,ATGP3904-100ug,ATGP3904-250ug,ATGP3904-500ug,ATGP3904-1mg,ATGP3904-10,ATGP3904-20,ATGP3904-50,ATGP3904-100,ATGP3904-250,ATGP3904-500,ATGP3904-1

more info or order :

NKMAX product webpage