Recombinant human Complement Factor B protein | NKMAX ATGP3903 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human Complement Factor B protein

catalog :

ATGP3903

quantity :

10 ug

price :

150 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human Complement Factor B protein

Domain :

260-764aa

Catalog number (SKU) :

ATGP3903

NCBI :

NP_001701

Description :

Complement factor B, also known as CFB, is a component of the alternative pathway of complement activation.Factor B circulates in the blood as a single chain polypeptide. Upon activation of the alternative pathway, itis cleaved by complement factor D yielding the noncatalytic chain Ba and the catalytic subunit Bb. The activesubunit Bb is a serine protease which associates with C3b to form the alternative pathway C3 convertase. Bb isinvolved in the proliferation of preactivated B lymphocytes, while Ba inhibits their proliferation. Recombinant human Complement factor B protein, fused to His-tag at C-terminus, was expressed in insect cell and purified byusing conventional chromatography techniques.

Alternative Names :

CFB, C3/C5 convertase, Glycine-rich beta glycoprotein, GBG, PBF2, Properdin factor B, BF, BFD, AHUS4, ARMD14, CFAB, CFBD, FB, FBI12, GBG, H2-Bf

Concentration :

0.5mg/ml (determined by absorbance at 280nm)

Formulation :

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 20% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Francis PJ., et al. (2009) J Med Genet. 46:300-307.;;Schwaeble W., et al (1993). Immunobiology 188:221-232.

Purity :

> 90% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Immunology

Molecular Weight :

58.1 kDa (514aa)

Endotoxin :

< 1 EU per 1ug of protein (determined by LAL method)

Amino Acid Sequence :

KIVLDPS GSMNIYLVLD GSDSIGASNF TGAKKCLVNL IEKVASYGVK PRYGLVTYAT YPKIWVKVSE ADSSNADWVT KQLNEINYED HKLKSGTNTK KALQAVYSMM SWPDDVPPEG WNRTRHVIIL MTDGLHNMGG DPITVIDEIR DLLYIGKDRK NPREDYLDVY VFGVGPLVNQ VNINALASKK DNEQHVFKVK DMENLEDVFY QMIDESQSLS LCGMVWEHRK GTDYHKQPWQ AKISVIRPSK GHESCMGAVV SEYFVLTAAH CFTVDDKEHS IKVSVGGEKR DLEIEVVLFH PNYNINGKKE AGIPEFYDYD VALIKLKNKL KYGQTIRPIC LPCTEGTTRA LRLPPTTTCQ QQKEELLPAQ DIKALFVSEE EKKLTRKEVY IKNGDKKGSC ERDAQYAPGY DKVKDISEVV TPRFLCTGGV SPYADPNTCR GDSGGPLIVH KRSRFIQVGV ISWGVVDVCK NQKRQKQVPA HARDFHINLF QVLPWLKEKL QDEDLGFL

Tag :

His-Tag

Expression System :

Baculovirus

Predicted nterm :

Ala

Product Type Name :

Recombinant Protein

UniProt No. :

P00751

Internal Search Terms :

Complement Factor B,ATGP3903-10ug,ATGP3903-20ug,ATGP3903-50ug,ATGP3903-100ug,ATGP3903-250ug,ATGP3903-500ug,ATGP3903-1mg,ATGP3903-10,ATGP3903-20,ATGP3903-50,ATGP3903-100,ATGP3903-250,ATGP3903-500,ATGP3903-1

more info or order :

NKMAX product webpage