product summary
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company name :
NKMAX
product type :
protein
product name :
Recombinant human Activin RIA/ALK-2 protein
catalog :
ATGP3898
quantity :
10 ug
price :
140 USD
more info or order :
product information
Product Type :
Proteins
Item Name :
Recombinant human Activin RIA/ALK-2 protein
Domain :
21-123aa
Catalog number (SKU) :
ATGP3898
NCBI :
NP_001096
Description :
Activin RIA, also known as Activin receptor type-1, is a member of TGF-beta serine/threonine kinase receptor family. It forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. This protein is involved for left-right pattern formation during embryogenesis. Also, it is important in the bone morphogenic protein (BMP) pathway which is responsible for the development and repair of the skeletal system. It has been connected to Fibrodysplasia Ossificans Progressiva, a disease characterized by the formation of heterotopic bone throughout the body. Recombinant Human Activin RIA, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Alternative Names :
ACVR1, ACTRI, ACVR1A, ACVRLK2, ALK2, FOP, SKR1, TSRI, Activin receptor type I, Activin receptor-like kinase 2, ACTR-I, ALK-2, TSR-I, Serine/threonine-protein kinase receptor R1, TGF-B superfamily receptor type I
Concentration :
0.25mg/ml (determined by absorbance at 280nm)
Formulation :
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Sorkin M., et al. (2017) Wound Repair Regen. 25:521-525.;; Schoenmaker T., et al. (2019) J Cell Physiol. 234:10238-10247.
Purity :
> 90% by SDS-PAGE
Applications :
SDS-PAGE
Antigen Species :
Human
Gene Category :
Cytoskeleton
Molecular Weight :
38.4 kDa (342aa)
Endotoxin :
< 1 EU per 1ug of protein (determined by LAL method)
Amino Acid Sequence :
MEDEKPKVNP KLYMCVCEGL SCGNEDHCEG QQCFSSLSIN DGFHVYQKGC FQVYEQGKMT CKTPPSPGQA VECCQGDWCN RNITAQLPTK GKSFPGTQNF HLE
Tag :
hIgG-His-Tag
Expression System :
Baculovirus
Predicted nterm :
Met21
Product Type Name :
Recombinant Protein
UniProt No. :
Q04771
Internal Search Terms :
Activin RIA, ALK2, ATGP3898-10ug,ATGP3898-20ug,ATGP3898-50ug,ATGP3898-100ug,ATGP3898-250ug,ATGP3898-500ug,ATGP3898-1mg, ATGP3898-10,ATGP3898-20,ATGP3898-50,ATGP3898-100,ATGP3898-250,ATGP3898-500,ATGP3898-1,ATGP3898-10ug,ATGP3898-20ug,ATGP3898-50ug,ATGP3898-100ug,ATGP3898-250ug,ATGP3898-500ug,ATGP3898-1mg,ATGP3898-10,ATGP3898-20,ATGP3898-50,ATGP3898-100,ATGP3898-250,ATGP3898-500,ATGP3898-1
more info or order :
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.