product summary
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company name :
NKMAX
product type :
protein
product name :
Recombinant human B7-2/CD86 protein
catalog :
ATGP3895
quantity :
10 ug
price :
70 USD
more info or order :
product information
Product Type :
Proteins
Item Name :
Recombinant human B7-2/CD86 protein
Domain :
31-247aa
Catalog number (SKU) :
ATGP3895
NCBI :
NP_787058
Description :
B7-2/CD86, also known as T-lymphocyte activation antigen CD86 isoform 1, is a variably glycosylated protein in the B7 family. These family members play important roles in immune activation and the maintenance of immune tolerance. It is expressed on antigen-presenting cells that provides costimulatory signals necessary for T cell activation and survival and exists predominantly as a monomer on cell surfaces. Also, it interacts with two co-stimulatory receptors CD28 and cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) expressed on T cells that it induces the signal pathways which regulate T cell activation and tolerance, cytokine production, and the generation of CTL. Recombinant Human B7-2/CD86, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Alternative Names :
B7-2/CD86, CD86, B7-2, B7.2, B70, CD28LG2, LAB72, T-lymphocyte activation antigen CD86, Activation B7-2 antigen, B70, BU63, CTLA-4 counter-receptor B7.2, FUN-1
Concentration :
0.5mg/ml (determined by absorbance at 280nm)
Formulation :
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Grujic M., et al, (2010) Journal of Immunology. 185 (3): 1730-1743.;;Kuchroo VK., et al, (1995) Cell 80:707-718.
Purity :
> 90% by SDS-PAGE
Applications :
SDS-PAGE
Antigen Species :
Human
Gene Category :
Immunology
Molecular Weight :
25.6 kDa (223aa)
Endotoxin :
< 1 EU per 1ug of protein (determined by LAL method)
Amino Acid Sequence :
YFNETADLPC QFANSQNQSL SELVVFWQDQ ENLVLNEVYL GKEKFDSVHS KYMGRTSFDS DSWTLRLHNL QIKDKGLYQC IIHHKKPTGM IRIHQMNSEL SVLANFSQPE IVPISNITEN VYINLTCSSI HGYPEPKKMS VLLRTKNSTI EYDGIMQKSQ DNVTELYDVS ISLSVSFPDV TSNMTIFCIL ETDKTRLLSS PFSIELEDPQ PPPDHIP
Tag :
His-Tag
Expression System :
Baculovirus
Predicted nterm :
Tyr31
Product Type Name :
Recombinant Protein
UniProt No. :
P42081
Internal Search Terms :
B72, CD86,ATGP3895-10ug,ATGP3895-20ug,ATGP3895-50ug,ATGP3895-100ug,ATGP3895-250ug,ATGP3895-500ug,ATGP3895-1mg, ATGP3895-10,ATGP3895-20,ATGP3895-50,ATGP3895-100,ATGP3895-250,ATGP3895-500,ATGP3895-1,ATGP3895-10ug,ATGP3895-20ug,ATGP3895-50ug,ATGP3895-100ug,ATGP3895-250ug,ATGP3895-500ug,ATGP3895-1mg,ATGP3895-10,ATGP3895-20,ATGP3895-50,ATGP3895-100,ATGP3895-250,ATGP3895-500,ATGP3895-1
more info or order :
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.