product summary
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company name :
NKMAX
product type :
protein
product name :
Recombinant human IFN-alpha/beta R1/IFNAR1 protein
catalog :
ATGP3894
quantity :
10 ug
price :
140 USD
more info or order :
product information
Product Type :
Proteins
Item Name :
Recombinant human IFN-alpha/beta R1/IFNAR1 protein
Domain :
28-436aa
Catalog number (SKU) :
ATGP3894
NCBI :
NP_000620
Description :
IFN-alpha/beta R1, also known as interferon alpha/beta receptor 1 (IFNAR1), is a member of the class II cytokine receptor family of proteins that form heterodimeric receptor complexes. These receptors are shared and served multiple functions. IFNAR1 and IFNBR1, in association with IFNAR2 and IFNBR2, is required for propagating anti-microbial signal transduction triggered by the type 1 interferons such as IFN-alpha and IFN-beta. Also, binding and activation of it stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2. Recombinant Human IFN-alpha/beta R1, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Alternative Names :
IFN-alpha/beta R1, IFNAR1, AVP, IFN-alpha-REC, IFNAR, IFNBR, IFRC, Interferon alpha/beta receptor 1,IFN-R-1, IFN-alpha/beta receptor 1, Cytokine receptor class-II member 1, Cytokine receptor family 2 member 1, CRF2-1, Type I interferon receptor 1
Concentration :
0.5mg/ml (determined by absorbance at 280nm)
Formulation :
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 20% glycerol
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Richter MF., et al, (1998) J Biol Chem. 273:24723-24729.;;Claudinon J., et al, (2009) J. Biol. Chem. 284:24328-24340.
Purity :
> 95% by SDS-PAGE
Applications :
SDS-PAGE
Antigen Species :
Human
Gene Category :
Hormones & Cytokines
Molecular Weight :
47.9 kDa (415aa)
Endotoxin :
< 1 EU per 1ug of protein (determined by LAL method)
Amino Acid Sequence :
KNLKSPQKVE VDIIDDNFIL RWNRSDESVG NVTFSFDYQK TGMDNWIKLS GCQNITSTKC NFSSLKLNVY EEIKLRIRAE KENTSSWYEV DSFTPFRKAQ IGPPEVHLEA EDKAIVIHIS PGTKDSVMWA LDGLSFTYSL VIWKNSSGVE ERIENIYSRH KIYKLSPETT YCLKVKAALL TSWKIGVYSP VHCIKTTVEN ELPPPENIEV SVQNQNYVLK WDYTYANMTF QVQWLHAFLK RNPGNHLYKW KQIPDCENVK TTQCVFPQNV FQKGIYLLRV QASDGNNTSF WSEEIKFDTE IQAFLLPPVF NIRSLSDSFH IYIGAPKQSG NTPVIQDYPL IYEIIFWENT SNAERKIIEK KTDVTVPNLK PLTVYCVKAR AHTMDEKLNK SSVFSDAVCE KTKPGNTSK
Tag :
His-Tag
Expression System :
Baculovirus
Predicted nterm :
Lys28
Product Type Name :
Recombinant Protein
UniProt No. :
P17181
Internal Search Terms :
IFN-a, b R1, ATGP3894-10ug,ATGP3894-20ug,ATGP3894-50ug,ATGP3894-100ug,ATGP3894-250ug,ATGP3894-500ug,ATGP3894-1mg, ATGP3894-10,ATGP3894-20,ATGP3894-50,ATGP3894-100,ATGP3894-250,ATGP3894-500,ATGP3894-1,ATGP3894-10ug,ATGP3894-20ug,ATGP3894-50ug,ATGP3894-100ug,ATGP3894-250ug,ATGP3894-500ug,ATGP3894-1mg,ATGP3894-10,ATGP3894-20,ATGP3894-50,ATGP3894-100,ATGP3894-250,ATGP3894-500,ATGP3894-1
more info or order :
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.