Recombinant human Ephrin-A3 protein | NKMAX ATGP3886 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human Ephrin-A3 protein

catalog :

ATGP3886

quantity :

10 ug

price :

70 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human Ephrin-A3 protein

Domain :

23-214aa

Catalog number (SKU) :

ATGP3886

NCBI :

NP_004943.1

Description :

Ephrin-A3, also known as EFNA3, is a member of the ephrin family. The ephrins and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, especially in the nervous system and in erythropoiesis. This protein activates EphA4 on hippocampal neurons to regulate dendritic spine morphology and long term potentiation. The same interaction induces reverse signaling through it to regulate glutamate uptake by the astrocyte and the availability of glutamate in the synapse. Astrocyte-expressed Ephrin-3 also interacts with EphA7 to inhibit the proliferation of neural progenitor cells. Recombinant human Ephrin-A3, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Alternative Names :

LERK3, EPLG3, Ephrin-A3, EPH-related receptor tyrosine kinase ligand 3, EHL1 ligand, EHK1-L, EFNA3, EFL2

Concentration :

0.5mg/ml (determined by absorbance at 280nm)

Formulation :

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Gomez-Maldonado L., et al. (2015 Oncogene. 34:2609-2620.;;Shukla A., et al. (2018) J Cell Biochem. 119:7934-7943.

Purity :

> 90% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Angiogenesis

Molecular Weight :

48.7 kDa (434aa)

Endotoxin :

< 1 EU per 1ug of protein (determined by LAL method)

Amino Acid Sequence :

QGPGGAL GNRHAVYWNS SNQHLRREGY TVQVNVNDYL DIYCPHYNSS GVGPGAGPGP GGGAEQYVLY MVSRNGYRTC NASQGFKRWE CNRPHAPHSP IKFSEKFQRY SAFSLGYEFH AGHEYYYIST PTHNLHWKCL RMKVFVCCAS TSHSGEKPVP TLPQFTMGPN VKINVLEDFE GENPQVPKLE KSISG

Tag :

hIgG-His-Tag

Expression System :

Baculovirus

Predicted nterm :

Ala

Product Type Name :

Recombinant Protein

UniProt No. :

P52797

Internal Search Terms :

LERK-3, LERK3, LERK 3, EPLG3, Ephrin-A3, EphrinA3, Ephrin A3, EPH-related receptor tyrosine kinase ligand 3, EPH related receptor tyrosine kinase ligand 3, EHL1 ligand, EHK1-L, EHK1 L, EFNA3, EFL-2, EFL2, EFL 2, ATGP3886-10ug, ATGP3886-20ug, ATGP3886-50ug, ATGP3886-100ug, ATGP3886-250ug, ATGP3886-500ug, ATGP3886-1mg, ATGP3886-010, ATGP3886-020, ATGP3886-050, ATGP3886-100, ATGP3886-250, ATGP3886-500, ATGP3886-01M

more info or order :

NKMAX product webpage