Recombinant human CX3CL1/Fractalkine protein | NKMAX ATGP3885 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human CX3CL1/Fractalkine protein

catalog :

ATGP3885

quantity :

10 ug

price :

120 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human CX3CL1/Fractalkine protein

Domain :

25-339aa

Catalog number (SKU) :

ATGP3885

NCBI :

NP_002987

Description :

CX3CL1, also known as fractalkine isoform 1, is a member of the CX3C chemokine family. It acts as a ligand for both CX3CR1 and integrins. This protein acts different ways dependent on its form. The soluble form is chemotactic for T-cells and monocytes and not for neutrophils. The membrane-bound form promotes adhesion of those leukocytes to endothelial cells. This protein plays a role in regulating leukocyte adhesion and migration processes at the endothelium. It is also up-regulated in the hippocampus during a brief temporal window following spatial learning, the purpose of which may be to regulate glutamate-mediated neurotransmission tone. This indicates a possible role for the chemokine in the protective plasticity process of synaptic scaling. Recombinant human CX3CL1, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography technique.

Alternative Names :

CX3CL1, ABCD-3, C3Xkine, CXC3, CXC3C, fractalkine, neurotactin, NTN, NTT, SCYD1, C-X3-C motif chemokine 1, CX3C membrane-anchored chemokine, Neurotactin, Small-inducible cytokine D1

Concentration :

1mg/ml (determined by absorbance at 280nm)

Formulation :

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Conroy MJ., et al. (2018) Front Immunol. 9:1867. ;;Hoffmann-Vold AM., et al. (2018) PLoS One. 13:e0206545.

Purity :

> 90% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Immunology

Molecular Weight :

34.3 kDa (323aa)

Endotoxin :

< 1 EU per 1ug of protein (determined by LAL method)

Amino Acid Sequence :

QHHGVTKCNI TCSKMTSKIP VALLIHYQQN QASCGKRAII LETRQHRLFC ADPKEQWVKD AMQHLDRQAA ALTRNGGTFE KQIGEVKPRT TPAAGGMDES VVLEPEATGE SSSLEPTPSS QEAQRALGTS PELPTGVTGS SGTRLPPTPK AQDGGPVGTE LFRVPPVSTA ATWQSSAPHQ PGPSLWAEAK TSEAPSTQDP STQASTASSP APEENAPSEG QRVWGQGQSP RPENSLEREE MGPVPAHTDA FQDWGPGSMA HVSVVPVSSE GTPSREPVAS GSWTPKAEEP IHATMDPQRL GVLITPVPDA QAATR

Tag :

His-Tag

Expression System :

Baculovirus

Predicted nterm :

Gln25

Product Type Name :

Recombinant Protein

UniProt No. :

P78423

Internal Search Terms :

CX3CL1, Fractalkine, ATGP3885-10ug,ATGP3885-20ug,ATGP3885-50ug,ATGP3885-100ug,ATGP3885-250ug,ATGP3885-500ug,ATGP3885-1mg, ATGP3885-10,ATGP3885-20,ATGP3885-50,ATGP3885-100,ATGP3885-250,ATGP3885-500,ATGP3885-1,ATGP3885-10ug,ATGP3885-20ug,ATGP3885-50ug,ATGP3885-100ug,ATGP3885-250ug,ATGP3885-500ug,ATGP3885-1mg,ATGP3885-10,ATGP3885-20,ATGP3885-50,ATGP3885-100,ATGP3885-250,ATGP3885-500,ATGP3885-1

more info or order :

NKMAX product webpage