product summary
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company name :
NKMAX
product type :
protein
product name :
Recombinant mouse IL-1Ra/IL1RN protein
catalog :
ATGP3884
quantity :
10 ug
price :
70 USD
more info or order :
product information
Product Type :
Proteins
Item Name :
Recombinant mouse IL-1Ra/IL1RN protein
Domain :
27-178aa
Catalog number (SKU) :
ATGP3884
NCBI :
NP_001034790
Description :
Interleukin 1 receptor antagonist (IL1RN), also known as IL1-RA, is a member of the interleukin 1 cytokine family. IL1RN may represent a reservoir of IL-1 inhibitors, released upon cell death, whose function is no limit the pro-inflammatory signals but most prominently by mononuclear phagocytes and keratinocytes. IL1RN is reported to be associated with increased risk of osteoporotic fractures and gastric cancer. Recombinant mouse IL1RN protein, fused to His-tag at N-terminus was expressed in E. coli and purified by using conventional chromatography techniques.
Alternative Names :
Interleukin-1 receptor antagonist protein, IL-1RN, IL-1ra, IRAP, IL1 inhibitor, IL1RA
Concentration :
1mg/ml (determined by Bradford assay)
Formulation :
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 10% glycerol
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Steinkasserer A., et al. (1992) Genomics. 13(3):654-7.;; Langdahl BL., et al. (2000) J Bone Miner Res. 15(3): 403-14.
Purity :
> 95% by SDS-PAGE
Bioactivity Comment Only :
Measured by its ability to inhibit proliferation using D10.G4.1 mouse helper T cells. The ED50 for this effect is less or equal to 60ng/ml with Mouse IL-1 alpha.
Applications :
SDS-PAGE, Bioactivity
Antigen Species :
Mouse
Gene Category :
Hormones & Cytokines
Additional Comment Only :
ATGP1516 has been replaced with a catalog number ATGP3884.
Molecular Weight :
20 kDa (177aa) confirmed by MALDI-TOF
Endotoxin :
< 1 EU per 1ug of protein (determined by LAL method)
Bioactivity Comment and Pics :
Mouse IL-1ra/IL-1F3 inhibits Mouse IL-1 alpha induced cell proliferation in the D10.G4.1 mouse helper T cell. The ED50 range is less or equal to 60 ng/ml.
Amino Acid Sequence :
RPSGK RPCKMQAFRI WDTNQKTFYL RNNQLIAGYL QGPNIKLEEK IDMVPIDLHS VFLGIHGGKL CLSCAKSGDD IKLQLEEVNI TDLSKNKEED KRFTFIRSEK GPTTSFESAA CPGWFLCTTL EADRPVSLTN TPEEPLIVTK FYFQEDQ
Tag :
His-Tag
Expression System :
E.coli
Product Type Name :
Recombinant Protein
UniProt No. :
P25085
Internal Search Terms :
ATGP1516, IL1ra, ICIL-1RA, IL1F3, ATGP3884-10ug, ATGP3884-20ug, ATGP3884-50ug, ATGP3884-100ug, ATGP3884-250ug, ATGP3884-500ug, ATGP3884-1mg, ATGP3884-010, ATGP3884-020, ATGP3884-050, ATGP3884-100, ATGP3884-250, ATGP3884-500, ATGP3884-01M, ATGP1516
more info or order :
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.