Recombinant mouse IL-15 protein | NKMAX ATGP3883 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant mouse IL-15 protein

catalog :

ATGP3883

quantity :

10 ug

price :

150 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant mouse IL-15 protein

Domain :

49-162aa

Catalog number (SKU) :

ATGP3883

NCBI :

NP_032383

Description :

Interleukin (IL) -15 is a pleiotropic cytokine that plays a pivotal role in both innate and adaptive immunity. IL-15 is unique among cytokines due to its participation in a trans signaling mechanism in which IL-15 receptor alpha (IL-15R alpha) from one subset of cells presents IL-15 to neighboring IL-2R beta/gamma (c) -expressing cells. This newly discovered cytokine is produced by a wide variety of cells and tissues and like IL-2, stimulates the proliferation of T-lymphocytes and induces the generation of cytotoxicT-lymphocytes (CTLs) and lymphokine-activated killer (LAK) cells. Recombinant Mouse IL-15 was expressed in E. coli and purified by using conventional chromatography techniques.

Alternative Names :

Interleukin-15

Concentration :

0.5mg/ml (determined by Bradford assay)

Formulation :

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

J G Giri., et al. (1994) EMBO. 13(12): 2822-2830.;;Lorenzen I., et al. (2006). J Biol Chem. 281(10):6642-7.

Purity :

> 90% by SDS-PAGE

Bioactivity Comment Only :

Measured in a cell proliferation assay using CTLL2 mouse cytotoxic T cells. The ED50 for this effect is less or equal to 20ng/ml.

Applications :

SDS-PAGE, Bioactivity

Antigen Species :

Mouse

Gene Category :

Hormones & Cytokines

Molecular Weight :

17.6 kDa (152aa) confirmed by MALDI-TOF

Endotoxin :

< 1 EU per 1ug of protein (determined by LAL method)

Bioactivity Comment and Pics :

Mouse IL-15 stimulates cell proliferation of the CTLL2 mouse cytotoxic T cells. The ED50 range is less or equal to 20 ng/ml.

Amino Acid Sequence :

NW IDVRYDLEKI ESLIQSIHID TTLYTDSDFH PSCKVTAMNC FLLELQVILH EYSNMTLNET VRNVLYLANS TLSSNKNVAE SGCKECEELE EKTFTEFLQS FIRIVQMFIN TS

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

P48346

Internal Search Terms :

IL15, IL 15, IL-15, Interleukin 15, Interleukin15, Interleukin-15, AI503618, MGC9721, IL-T, Interleukin-15 precursor, OTTHUMP00000164617, ATGP3883-10ug, ATGP3883-20ug, ATGP3883-50ug, ATGP3883-100ug, ATGP3883-250ug, ATGP3883-500ug, ATGP3883-1mg, ATGP3883-010, ATGP3883-020, ATGP3883-050, ATGP3883-100, ATGP3883-250, ATGP3883-500, ATGP3883-01M

more info or order :

NKMAX product webpage