product summary
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company name :
NKMAX
product type :
protein
product name :
Recombinant mouse TSLP protein
catalog :
ATGP3879
quantity :
10 ug
price :
185 USD
more info or order :
product information
Product Type :
Proteins
Item Name :
Recombinant mouse TSLP protein
Domain :
20-140aa
Catalog number (SKU) :
ATGP3879
NCBI :
NP_067342
Description :
TSLP, also known as thymic stromal lymphopoietin, is a protein belonging to the cytokine family. This protein plays an important role in the maturation of T cell populations through activation of antigen presenting cells. It is an interleukin 7-like cytokine originally characterized by its ability to promote the activation of B cells and dendritic cells (DCs). It is expressed by non-hematopoietic cells such as fibroblasts, epithelial cells and different types of stromal or stromal-like cells, and is important in allergic inflammation. It signals through a heterodimeric receptor complex composed of the thymic stromal lymphopoietin receptor CRLF2 and the IL-7R alpha chain. After binding STAT5 phosphorylation is induced resulting in the expression of upstream transcription factors. Also, expression of TSLP is linked to many disease states including asthma, inflammatory arthritis, atopic dermatitis, eczema, eosinophilic esophagitis and other allergic states. But the factors are not clearly defined. Recombinant Mouse TSLP, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Alternative Names :
Thymic stromal lymphopoietin, Thymic stroma-derived lymphopoietin, Tslp
Concentration :
0.5mg/ml (determined by absorbance at 280nm)
Formulation :
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Sims JE., et al, (2000) J. Exp. Med. 192:671-680.;;Pandey A., et al, (2000) Nautre Immunol. 1:59.
Purity :
> 90% by SDS-PAGE
Applications :
SDS-PAGE
Antigen Species :
Mouse
Gene Category :
Immunology
Molecular Weight :
15kDa (130aa)
Endotoxin :
< 1 EU per 1ug of protein (determined by LAL method)
Amino Acid Sequence :
YNFSNCN FTSITKIYCN IIFHDLTGDL KGAKFEQIED CESKPACLLK IEYYTLNPIP GCPSLPDKTF ARRTREALND HCPGYPETER NDGTQEMAQE VQNICLNQTS QILRLWYSFM QSPE
Tag :
His-Tag
Expression System :
Baculovirus
Predicted nterm :
Ala
Product Type Name :
Recombinant Protein
UniProt No. :
Q9JIE6
Internal Search Terms :
TSLP,ATGP3879-10ug,ATGP3879-20ug,ATGP3879-50ug,ATGP3879-100ug,ATGP3879-250ug,ATGP3879-500ug,ATGP3879-1mg,ATGP3879-10,ATGP3879-20,ATGP3879-50,ATGP3879-100,ATGP3879-250,ATGP3879-500,ATGP3879-1
more info or order :
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.