Recombinant mouse CD200 protein | NKMAX ATGP3878 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant mouse CD200 protein

catalog :

ATGP3878

quantity :

50 ug

price :

185 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant mouse CD200 protein

Domain :

31-232aa

Catalog number (SKU) :

ATGP3878

NCBI :

NP_034948

Description :

CD200, also known as OX-2 membrane glycoprotein isoform 1, is one of the immunoglobulin superfamily. It plays an important role in anti-tumor immunity through interaction with its receptor, and overexpression of this protein effects on malignancies as well as on cancer stem cells. In T cells, this protein functions as a co-stimulatory effect that is independent of the CD28 pathway. It also plays an important role on myeloid cell regulation that is suggested by restricted expression of its receptor. Studies of this protein in mouse and rat suggest that this gene may regulate myeloid cell activity and delivers an inhibitory signal for the macrophage lineage in diverse tissues. Recombinant mouse CD200, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Alternative Names :

Cd200, Mox2, OX2, OX-2 membrane glycoprotein isoform 1, MRC OX-2 antigen

Concentration :

1mg/ml (determined by absorbance at 280nm)

Formulation :

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Poongodi R., et al. (2018) Indian J Pathol Microbiol. 61:50-57. ;;Kuwabara J., et al. (2018) Biochem Biophys Res Commun. 496:542-548.

Purity :

> 95% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Mouse

Gene Category :

Immunology

Molecular Weight :

49.5 kDa (441aa)

Endotoxin :

< 1 EU per 1ug of protein (determined by LAL method)

Amino Acid Sequence :

QVEVVTQDER KALHTTASLR CSLKTSQEPL IVTWQKKKAV SPENMVTYSK THGVVIQPAY KDRINVTELG LWNSSITFWN TTLEDEGCYM CLFNTFGSQK VSGTACLTLY VQPIVHLHYN YFEDHLNITC SATARPAPAI SWKGTGTGIE NSTESHFHSN GTTSVTSILR VKDPKTQVGK EVICQVLYLG NVIDYKQSLD KG

Tag :

hIgG-His-Tag

Expression System :

Baculovirus

Predicted nterm :

Gln31

Product Type Name :

Recombinant Protein

UniProt No. :

O54901

Internal Search Terms :

CD200,ATGP3878-10ug,ATGP3878-20ug,ATGP3878-50ug,ATGP3878-100ug,ATGP3878-250ug,ATGP3878-500ug,ATGP3878-1mg,ATGP3878-10,ATGP3878-20,ATGP3878-50,ATGP3878-100,ATGP3878-250,ATGP3878-500,ATGP3878-1

more info or order :

NKMAX product webpage