product summary
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company name :
NKMAX
product type :
protein
product name :
Recombinant mouse Neutrophil Elastase/ELA2 protein
catalog :
ATGP3873
quantity :
10 ug
price :
150 USD
more info or order :
product information
Product Type :
Proteins
Item Name :
Recombinant mouse Neutrophil Elastase/ELA2 protein
Domain :
27-265aa
Catalog number (SKU) :
ATGP3873
NCBI :
NP_056594.2
Description :
Neutrophil Elastase, also known as polymorphonuclear leukocyte eslastase, is a serine protease that classified as the chymotrypsin family. This protein breaks down elastin, an elastic fiber together with collagen and determines the mechanical properties of connective tissue. The neutrophil form breaks down the Outer membrane protein A (OmpA) of E. coli and other Gram-negative bacteria. Also, this protein is inhibited by the acute-phase protein alpha 1-antitrypsin (A1AT), which binds almost irreversibly to the active site of elastase and trypsin. A1AT is normally secreted by the liver cells into the serum. Alpha-1-antitrypsin deficiency (A1AD) leads to uninhibited destruction of elastic fiber by elastase. Recombinant Mouse Neutrophil Elastase, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Alternative Names :
Elane, Ela2, F430011M15Rik, NE, Neutrophil elastase, Elastase-2, Leukocyte elastase
Concentration :
0.25mg/ml (determined by absorbance at 280nm)
Formulation :
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 30% glycerol
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Wiesmeier M., et al, (2016) PLoS ONE 11:e0168055.;;Sturrock A., et al, (1998) Cytogenet. Cell Genet. 83:104-108.
Purity :
> 90% by SDS-PAGE
Applications :
SDS-PAGE
Antigen Species :
Mouse
Gene Category :
Immunology
Molecular Weight :
26.8 kDa (245aa)
Endotoxin :
< 1 EU per 1ug of protein (determined by LAL method)
Amino Acid Sequence :
SEIVGGRPAR PHAWPFMASL QRRGGHFCGA TLIARNFVMS AAHCVNGLNF RSVQVVLGAH DLRRQERTRQ TFSVQRIFEN GFDPSQLLND IVIIQLNGSA TINANVQVAQ LPAQGQGVGD RTPCLAMGWG RLGTNRPSPS VLQELNVTVV TNMCRRRVNV CTLVPRRQAG ICFGDSGGPL VCNNLVQGID SFIRGGCGSG LYPDAFAPVA EFADWINSII RSHNDHLLTH PKDREGRTN
Tag :
His-Tag
Expression System :
Baculovirus
Predicted nterm :
Ser27
Product Type Name :
Recombinant Protein
UniProt No. :
Q3UP87
Internal Search Terms :
Neutrophil Elastase, ELA2,ATGP3873-10ug,ATGP3873-20ug,ATGP3873-50ug,ATGP3873-100ug,ATGP3873-250ug,ATGP3873-500ug,ATGP3873-1mg,ATGP3873-10,ATGP3873-20,ATGP3873-50,ATGP3873-100,ATGP3873-250,ATGP3873-500,ATGP3873-1
more info or order :
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.