Recombinant human IL-1 alpha/IL1A protein | NKMAX ATGP3864 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human IL-1 alpha/IL1A protein

catalog :

ATGP3864

quantity :

10 ug

price :

150 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human IL-1 alpha/IL1A protein

Domain :

113-271aa

Catalog number (SKU) :

ATGP3864

NCBI :

NP_000566

Description :

IL-1 consists of two distinct forms, IL-1 alpha and IL-1 beta which perform the same functions but are distinct proteins. IL-1alpha is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis. This cytokine is also temporarily upregulated during bone formation and the menstrual cycle and can be induced in response to nervous system stimulation. Recombinant human IL-1alpha was expressed in E.coli and purified by using conventional chromatography techniques.

Alternative Names :

Interleukin 1 alpha, preinterleukin 1 alpha, Hematopoietin-1, Pro-interleukin-1-alpha, IL1F1, IL-1A, IL1-ALPHA, IL1

Concentration :

1mg/ml (determined by absorbance at 280nm)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 7.5) containing 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Misener VL., et al. (2008). Neuropsychobiology. 58(2):71-80.;;Sarkar O., et al. (2008). Biol Reprod. 78(3):445-54.

Purity :

> 90% by SDS-PAGE

Bioactivity Comment Only :

Measured in a cell proliferation assay using D10.G4.1 mouse helper T cell. The ED50 for this effect is less or equal to 0.04ng/ml.

Applications :

SDS-PAGE, Bioactivity

Antigen Species :

Human

Gene Category :

Hormones & Cytokines

Molecular Weight :

22.4 kDa (197aa) confirmed by MALDI-TOF

Endotoxin :

< 1 EU per 1ug of protein (determined by LAL method)

Bioactivity Comment and Pics :

Human IL-1 alpha /IL-1F1 stimulates cell proliferation of the D10.G4.1 mouse helper T cell. The ED50 range is less or equal to 0.04 ng/ml.

Amino Acid Sequence :

SA PFSFLSNVKY NFMRIIKYEF ILNDALNQSI IRANDQYLTA AALHNLDEAV KFDMGAYKSS KDDAKITVIL RISKTQLYVT AQDEDQPVLL KEMPEIPKTI TGSETNLLFF WETHGTKNYF TSVAHPNLFI ATKQDYWVCL AGGPPSITDF QILENQA

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

P01583

Internal Search Terms :

IL1 a , IL1F1,ATGP3864-10ug,ATGP3864-20ug,ATGP3864-50ug,ATGP3864-100ug,ATGP3864-250ug,ATGP3864-500ug,ATGP3864-1mg,ATGP3864-10,ATGP3864-20,ATGP3864-50,ATGP3864-100,ATGP3864-250,ATGP3864-500,ATGP3864-1

more info or order :

NKMAX product webpage