product summary
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company name :
NKMAX
product type :
protein
product name :
Recombinant human CTHRC1 protein
catalog :
ATGP3863
quantity :
10 ug
price :
120 USD
more info or order :
NKMAX product webpage
product information
Product Type :
Proteins
Item Name :
Recombinant human CTHRC1 protein
Domain :
31-243aa
Catalog number (SKU) :
ATGP3863
NCBI :
NP_612464
Description :
CTHRC1, also known as collagen triple helix repeat-containing protein 1 isoform 1, is a secreted glycoprotein that is expressed on renal epithelium, neurons, osteoblasts, and smooth muscle cells. This protein is overexpressed in different kinds of cancer tissues and promotes tumor formation. It acts as a negative regulator of collagen matrix deposition and is involved in cell migration, motility and invasion. The hormonal functions of CTHRC1 include regulation of lipid storage and cellular glycogen levels with potentially far-reaching implications for cell metabolism and physiology. Additionally, CTHRC1 increases bone mass as a positive regulator of osteoblastic bone formation and offers an anabolic approach for the treatment of osteoporosis. Recombinant human CTHRC1, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Alternative Names :
Collagen triple helix repeat-containing protein 1 isoform 1, CTHRC1, Protein NMTC1
Concentration :
0.5mg/ml (determined by absorbance at 280nm)
Formulation :
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Jin YR., et al. (2017) Bone. 97:153-167. ;; He W., et al. (2018) BMC Cancer. 18:400. doi
Purity :
> 90% by SDS-PAGE
Applications :
SDS-PAGE
Antigen Species :
Human
Gene Category :
Cytoskeleton
Molecular Weight :
24.1 kDa (222aa)
Endotoxin :
< 1 EU per 1ug of protein (determined by LAL method)
Amino Acid Sequence :
SEIPKGK QKAQLRQREV VDLYNGMCLQ GPAGVPGRDG SPGANGIPGT PGIPGRDGFK GEKGECLRES FEESWTPNYK QCSWSSLNYG IDLGKIAECT FTKMRSNSAL RVLFSGSLRL KCRNACCQRW YFTFNGAECS GPLPIEAIIY LDQGSPEMNS TINIHRTSSV EGLCEGIGAG LVDVAIWVGT CSDYPKGDAS TGWNSVSRII IEELPK
Tag :
His-Tag
Expression System :
Baculovirus
Predicted nterm :
Ala
Product Type Name :
Recombinant Protein
UniProt No. :
Q96CG8
Internal Search Terms :
CTHRC1,ATGP3863-10ug,ATGP3863-20ug,ATGP3863-50ug,ATGP3863-100ug,ATGP3863-250ug,ATGP3863-500ug,ATGP3863-1mg,ATGP3863-10,ATGP3863-20,ATGP3863-50,ATGP3863-100,ATGP3863-250,ATGP3863-500,ATGP3863-1
more info or order :
NKMAX product webpage
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.