Recombinant human Carboxylesterase 1/CES1 protein | NKMAX ATGP3862 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human Carboxylesterase 1/CES1 protein

catalog :

ATGP3862

quantity :

10 ug

price :

350 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human Carboxylesterase 1/CES1 protein

Domain :

19-568aa

Catalog number (SKU) :

ATGP3862

NCBI :

NP_001020366

Description :

Carboxylesterase 1, also known as liver carboxylesterase 1 isoform a, is a member of a large family of carboxylesterases. It is also part of the alpha/beta fold hydrolase family. Carboxylesterases hydrolyze long-chain fatty acid esters and thioesters. The resulting carboxylates are then often conjugated by other enzymes to increase solubility and eventually excreted. Also, this enzyme may play a role in detoxification in the lung and/or protection of the central nervous system from ester or amide compounds. This protein is known to react aromatic and aliphatic esters and can manage cellular cholesterol esterification levels. It is present in most tissues with higher levels in the liver and low levels in the gastrointestinal tract. Recombinant human Carboxylesterase 1, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Alternative Names :

Liver carboxylesterase 1 isoform a, CES1, ACAT, CE-1, CEH, CES2, hCE-1, HMSE, HMSE1, PCE-1, REH, SES1, TGH

Concentration :

0.5mg/ml (determined by absorbance at 280nm)

Formulation :

Liquid in. 25mM Sodium Acetate (pH 4.0) containing 10% glycerol, 0.1M NaCl, 0.1mM PMSF

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Satoh T., et al, (2006) Chem Biol Interact. 162:195-211.;;Redinbo MR., et al. (2005) Drug Discovery Today 10:313.

Purity :

> 90% by SDS-PAGE

Bioactivity Comment Only :

Specific activity is > 700pmol/min/ug and is defined as the amount of enzyme that hydrolyze 1pmole of p-nitrophenyl acetate to pnitrophenol per minute at pH 7.5 at 37C.

Applications :

Enzyme Activity,SDS-PAGE

Antigen Species :

Human

Gene Category :

Cardiovascular

Molecular Weight :

61.7 kDa (559aa)

Endotoxin :

< 1 EU per 1ug of protein (determined by LAL method)

Bioactivity Comment and Pics :

Specific activity is > 700 pmol/min/ug and is defined as the amount of enzyme that hydrolyze 1pmole of p-nitrophenyl acetate to pnitrophenol per minute at pH 7.5 at 37C.

Amino Acid Sequence :

ADLGHPSSPP VVDTVHGKVL GKFVSLEGFA QPVAIFLGIP FAKPPLGPLR FTPPQPAEPW SFVKNATSYP PMCTQDPKAG QLLSELFTNR KENIPLKLSE DCLYLNIYTP ADLTKKNRLP VMVWIHGGGL MVGAASTYDG LALAAHENVV VVTIQYRLGI WGFFSTGDEH SRGNWGHLDQ VAALRWVQDN IASFGGNPGS VTIFGESAGG ESVSVLVLSP LAKNLFHRAI SESGVALTSV LVKKGDVKPL AEQIAITAGC KTTTSAVMVH CLRQKTEEEL LETTLKMKFL SLDLQGDPRE SQPLLGTVID GMLLLKTPEE LQAERNFHTV PYMVGINKQE FGWLIPMQLM SYPLSEGQLD QKTAMSLLWK SYPLVCIAKE LIPEATEKYL GGTDDTVKKK DLFLDLIADV MFGVPSVIVA RNHRDAGAPT YMYEFQYRPS FSSDMKPKTV IGDHGDELFS VFGAPFLKEG ASEEEIRLSK MVMKFWANFA RNGNPNGEGL PHWPEYNQKE GYLQIGANTQ AAQKLKDKEV AFWTNLFAKK AVEKPPQTEH IELHHHHHH

Tag :

His-Tag

Expression System :

Baculovirus

Predicted nterm :

Ala

Product Type Name :

Recombinant Protein

UniProt No. :

P23141

Internal Search Terms :

Carboxylesterase1, CES1, Carboxylesterase 1/CES1Liver carboxylesterase 1 isoform a, CES1, ACAT, CE-1, CEH, CES2, hCE-1, HMSE, HMSE1, PCE-1, REH, SES1, TGH,ATGP3862-10ug,ATGP3862-20ug,ATGP3862-50ug,ATGP3862-100ug,ATGP3862-250ug,ATGP3862-500ug,ATGP3862-1mg,ATGP3862-10,ATGP3862-20,ATGP3862-50,ATGP3862-100,ATGP3862-250,ATGP3862-500,ATGP3862-1

more info or order :

NKMAX product webpage