Recombinant human FGF receptor 1/FGFR1 protein | NKMAX ATGP3856 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human FGF receptor 1/FGFR1 protein

catalog :

ATGP3856

quantity :

10 ug

price :

66 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human FGF receptor 1/FGFR1 protein

Domain :

22-374aa

Catalog number (SKU) :

ATGP3856

NCBI :

NP_056934

Description :

FGF R1 alpha, also known as fibroblast growth factor receptor 1 isoform 2, is a receptor tyrosine kinase whose ligands are specific members of the fibroblast growth factor family. This protein is related fibroblast growth factor (FGF) receptors that are involved in physiological and pathological processes such as cell division, regulation of cell growth and maturation, formation of blood vessels and embryonic developments. The biological activities of the FGFs are meditated by a family of type 1 transmembrane tyrosine kinases which undergo dimerization and auto-phosphorylation after ligand binding. Also, this protein is thought to play an important role in the development of the nervous system. It may also help regulate the growth of long bones, such as the large bones in the arms and legs. Defects in FGF R1 alpha are associated with various congenital malformations of the musculoskeletal system: these include the Pfeiffer syndrome, Jackson-Weiss syndrome, Antley-Bixler syndrome. Recombinant human FGF R1 alpha, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Alternative Names :

Fibroblast growth factor receptor 1 isoform 1, FGFR-1, Basic fibroblast growth factor receptor 1, BFGFR, bFGF-R-1, Fms-like tyrosine kinase 2, FLT-2, N-sam, Proto-oncogene c-Fgr, CD331, CEK, FGFBR, FLG, HBGFR, KAL2, Pfeiffer syndrome

Concentration :

0.5mg/ml (determined by absorbance at 280nm)

Formulation :

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Galzie Z., et al, (1997) Biochem. Cell Biol. 75:669-685.;;Burke D., et al, (1998) Trands Biochem Sci. 23:59-62.

Purity :

> 95% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Cardiovascular

Molecular Weight :

40.1 kDa (361aa)

Endotoxin :

< 1 EU per 1ug of protein (determined by LAL method)

Amino Acid Sequence :

RPSPTLPEQA QPWGAPVEVE SFLVHPGDLL QLRCRLRDDV QSINWLRDGV QLAESNRTRI TGEEVEVQDS VPADSGLYAC VTSSPSGSDT TYFSVNVSDA LPSSEDDDDD DDSSSEEKET DNTKPNPVAP YWTSPEKMEK KLHAVPAAKT VKFKCPSSGT PNPTLRWLKN GKEFKPDHRI GGYKVRYATW SIIMDSVVPS DKGNYTCIVE NEYGSINHTY QLDVVERSPH RPILQAGLPA NKTVALGSNV EFMCKVYSDP QPHIQWLKHI EVNGSKIGPD NLPYVQILKT AGVNTTDKEM EVLHLRNVSF EDAGEYTCLA GNSIGLSHHS AWLTVLEALE ERPAVMTSPL YLE

Tag :

His-Tag

Expression System :

Baculovirus

Predicted nterm :

Arg22

Product Type Name :

Recombinant Protein

UniProt No. :

P11362

Internal Search Terms :

FGF R1 a, FGF R1 alphaFibroblast growth factor receptor 1 isoform 2, FGFR 1a, bFGF-R-1, BFGFR, CD331, CEK, ECCL, FGFBR, FGFR-1, FLG, FLT-2, FLT2, HBGFR, HH2, HRTFDS, KAL2, N-SAM, OGD,ATGP3856-10ug,ATGP3856-20ug,ATGP3856-50ug,ATGP3856-100ug,ATGP3856-250ug,ATGP3856-500ug,ATGP3856-1mg,ATGP3856-10,ATGP3856-20,ATGP3856-50,ATGP3856-100,ATGP3856-250,ATGP3856-500,ATGP3856-1

more info or order :

NKMAX product webpage