Recombinant human Chemerin protein | NKMAX ATGP3855 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human Chemerin protein

catalog :

ATGP3855

quantity :

10 ug

price :

120 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human Chemerin protein

Domain :

21-157aa

Catalog number (SKU) :

ATGP3855

NCBI :

NP_002880.1

Description :

Chemerin, also known as retinoic acid receptor responder protein 2 (RARRES2), is a distant member of the Cystatin superfamily. It is involved in multiple cancers, including adrenocortical carcinoma (ACC). This protein in serum is transcriptionally downregulated in multiple cancer types. On the other hands, overexpression of this protein inhibits Wnt/beta-catenin pathway activity by promoting beta-catenin phosphorylation and degradation. Also, it has been implicated in autocrine/paracrine signaling for adipocyte differentiation and also stimulation of lipolysis. It was found to stimulate chemotaxis of dendritic cells and macrophages to the site of inflammation. Recombinant human Chemerin protein, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Alternative Names :

Retinoic acid receptor responder protein 2, RARRES2, HP10433, TIG2

Concentration :

0.5mg/ml (determined by absorbance at 280nm)

Formulation :

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Reverchon M., et al, (2014) Biol Reprod. 90:102.;;Liu-Chittenden Y., et al, (2016) J Clin Endocrinol Metab. 101(9):3345-3352.

Purity :

> 90% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Cardiovascular

Molecular Weight :

16.6 kDa (143aa)

Endotoxin :

< 1 EU per 1ug of protein (determined by LAL method)

Amino Acid Sequence :

ELTEAQRRGL QVALEEFHKH PPVQWAFQET SVESAVDTPF PAGIFVRLEF KLQQTSCRKR DWKKPECKVR PNGRKRKCLA CIKLGSEDKV LGRLVHCPIE TQVLREAEEH QETQCLRVQR AGEDPHSFYF PGQFAFS

Tag :

His-Tag

Expression System :

HEK293

Predicted nterm :

Glu21

Product Type Name :

Recombinant Protein

UniProt No. :

Q99969

Internal Search Terms :

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more info or order :

NKMAX product webpage