product summary
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company name :
NKMAX
product type :
protein
product name :
Recombinant human Angiopoietin 2/ANGPT2 protein
catalog :
ATGP3853
quantity :
20 ug
price :
200 USD
more info or order :
product information
Product Type :
Proteins
Item Name :
Recombinant human Angiopoietin 2/ANGPT2 protein
Domain :
19-496aa
Catalog number (SKU) :
ATGP3853
NCBI :
NP_001138
Description :
Angiopoietin-2, also known as ANGPT2, is a member of the ANG family. It has been identified as ligands for vascular endothelial-specific Tie2 receptor tyrosine kinase that interact with ANG2. This protein may be important growth factors in the generation of new blood vessels. Also, it is over-expression disrupts blood vessel formation in the mouse embryo. This protein is strongly expressed only at sites of vascular remodeling. It has been suggested that it may act synergistically with other cytokines such as vascular endothelial growth factor to promote tumor-associated Angiogenesis and tumor progression. Recombinant human Angiopoietin-2 fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Alternative Names :
Angiopoietin-2 isoform a, ANGPT2, AGPT2, ANG2
Concentration :
0.25mg/ml (determined by absorbance at 280nm)
Formulation :
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Maisonpierre PC., et al. (1997) Science. 277:55-60.;;Nowicki M., et al. (2017) Ann Hematol. 96:2103-2112.
Purity :
> 90% by SDS-PAGE
Bioactivity Comment Only :
Measured by its binding ability in a functional ELISA with Human TIE-2 (CAT# ATGP3947)
Applications :
SDS-PAGE, Bioactivity
Antigen Species :
Human
Gene Category :
Angiogenesis
Molecular Weight :
55.7 kDa (484aa)
Endotoxin :
< 1 EU per 1ug of protein (determined by LAL method)
Bioactivity Comment and Pics :
Human Angiopoietin-2 is coated at 5 ug/ml (100 ul/well) can bind Human TIE-2 (CAT# ATGP3947) in a Functional ELISA assay.
Amino Acid Sequence :
YNNFRKSMDS IGKKQYQVQH GSCSYTFLLP EMDNCRSSSS PYVSNAVQRD APLEYDDSVQ RLQVLENIME NNTQWLMKLE NYIQDNMKKEMVEIQQNAVQ NQTAVMIEIG TNLLNQTAEQ TRKLTDVEAQ VLNQTTRLEL QLLEHSLSTN KLEKQILDQT SEINKLQDKN SFLEKKVLAMEDKHIIQLQS IKEEKDQLQV LVSKQNSIIE ELEKKIVTAT VNNSVLQKQQ HDLMETVNNL LTMMSTSNSA KDPTVAKEEQ ISFRDCAEVFKSGHTTNGIY TLTFPNSTEE IKAYCDMEAG GGGWTIIQRR EDGSVDFQRT WKEYKVGFGN PSGEYWLGNE FVSQLTNQQR YVLKIHLKDWEGNEAYSLYE HFYLSSEELN YRIHLKGLTG TAGKISSISQ PGNDFSTKDG DNDKCICKCS QMLTGGWWFD ACGPSNLNGM YYPQRQNTNKFNGIKWYYWK GSGYSLKATT MMIRPADF
Tag :
His-Tag
Expression System :
CHO Cell
Predicted nterm :
Tyr19
Product Type Name :
Recombinant Protein
UniProt No. :
O15123
Internal Search Terms :
Angiopoietin2,ATGP3853-10ug,ATGP3853-20ug,ATGP3853-50ug,ATGP3853-100ug,ATGP3853-250ug,ATGP3853-500ug,ATGP3853-1mg,ATGP3853-10,ATGP3853-20,ATGP3853-50,ATGP3853-100,ATGP3853-250,ATGP3853-500,ATGP3853-1
more info or order :
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.