Recombinant mouse TRANCE/RANKL/TNFSF11 protein | NKMAX ATGP3851 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant mouse TRANCE/RANKL/TNFSF11 protein

catalog :

ATGP3851

quantity :

20 ug

price :

190 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant mouse TRANCE/RANKL/TNFSF11 protein

Domain :

158-316aa

Catalog number (SKU) :

ATGP3851

NCBI :

NP_035743

Description :

TRANCE, also known as tumor necrosis factor ligand superfamily member 11, is a member of the tumor necrosis factor (TNF) cytokine family which is a ligand for osteoprotegerin and functions as a key factor for osteoclast differentiation and activation. TRANCE also has a function in the immune system, where it is expressed by T helper cells and is thought to be involved in dendritic cell maturation. TRANCE is important in bone metabolism. This natural and necessary surface-bound molecule (also known as CD254) found on osteoblasts serves to activate osteoclasts, which are the cells involved in bone resorption. Recombinant Mouse TRANCE protein was expressed in E. coli and purified by using conventional chromatography.

Alternative Names :

Tumor necrosis factor ligand superfamily member 11, Osteoclast differentiation factor, ODF, Osteoprotegerin ligand, OPGL, Receptor activator of nuclear factor kappa-B ligand, RANKL, TNF-related activation-induced cytokine, TRANCE, CD254

Concentration :

1mg/ml (determined by Bradford assay)

Formulation :

Liquid In. 20mM Tris-HCl buffer (pH8.5) containing 0.1M NaCl

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Lam J., et al. (2001). J. Clin. Invest. 108(7):971-9;;Ito S., et al. (2002). J. Biol. Chem. 277(8):6631-6

Purity :

> 90% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Mouse

Gene Category :

Hormones & Cytokines

Molecular Weight :

17.9 kDa (160aa) confirmed by MALDI-TOF

Endotoxin :

< 1 EU per 1ug of protein (determined by LAL method)

Amino Acid Sequence :

MKPEAQPFAH LTINAASIPS GSHKVTLSSW YHDRGWAKIS NMTLSNGKLR VNQDGFYYLY ANICFRHHET SGSVPTDYLQ LMVYVVKTSI KIPSSHNLMK GGSTKNWSGN SEFHFYSINV GGFFKLRAGE EISIQVSNPS LLDPDQDATY FGAFKVQDID

Tag :

Non-Tagged

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

O35235

Internal Search Terms :

TRANCE, RANK L, TNFSF11,ATGP3851-10ug,ATGP3851-20ug,ATGP3851-50ug,ATGP3851-100ug,ATGP3851-250ug,ATGP3851-500ug,ATGP3851-1mg,ATGP3851-10,ATGP3851-20,ATGP3851-50,ATGP3851-100,ATGP3851-250,ATGP3851-500,ATGP3851-1

more info or order :

NKMAX product webpage