Recombinant human Vitronectin protein | NKMAX ATGP3849 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human Vitronectin protein

catalog :

ATGP3849

quantity :

50 ug

price :

60 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human Vitronectin protein

Domain :

20-478aa

Catalog number (SKU) :

ATGP3849

NCBI :

NP_000629.3

Description :

Vitronectin, also known VTN, is a member of the pexin family. It is a cell adhesion and spreading factor found in serum and tissues. This protein interacts with glycosaminoglycans and proteoglycans and is recognized by certain members of the integrin family and serves as a cell-to-substrate adhesion molecule. It also contains endogenous cleavage sites such as elastase, thrombin and plasmin. This protein binds multiple ligands, including the soluble vitronectin receptor which affects multi-function. Therefore, it is involved in hemostasis, cell migration, as well as tumor malignancy. Recombinant human Vitronectin protein, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Alternative Names :

VTN, VN, S-protein, Serum-spreading factor, V75, Vitronectin V65 subunit, Vitronectin V10 subunit, Somatomedin-B, Somatomedin B, Complement S-protein

Concentration :

0.25mg/ml (determined by Bradford assay)

Formulation :

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Yang XP., et al, (2016) Cancer Biomark. 17:271-279.;;Min SK., et al, (2017) Cell Death Differ. 25:268-281.

Purity :

> 90% by SDS-PAGE

Bioactivity Comment Only :

Measured by the ability of the immobilized protein to support the adhesion of B16-F10 mouse melanoma cells. When cells are added to VTN coated plates 5ug/ml. This effect is more to 50%.

Applications :

SDS-PAGE, Bioactivity

Antigen Species :

Human

Gene Category :

Cardiovascular

Molecular Weight :

53.3 kDa (468aa)

Endotoxin :

< 0.1 EU per 1ug of protein (determined by LAL method)

Bioactivity Comment and Pics :

Measured by the ability of the immobilized protein to support the adhesion of B16-F10 mouse melanoma cells. When cells are added to VTN coated plates 5ug/ml. This effect is more to 50%.

Amino Acid Sequence :

DQESCKG RCTEGFNVDK KCQCDELCSY YQSCCTDYTA ECKPQVTRGD VFTMPEDEYT VYDDGEEKNN ATVHEQVGGP SLTSDLQAQS KGNPEQTPVL KPEEEAPAPE VGASKPEGID SRPETLHPGR PQPPAEEELC SGKPFDAFTD LKNGSLFAFR GQYCYELDEK AVRPGYPKLI RDVWGIEGPI DAAFTRINCQ GKTYLFKGSQ YWRFEDGVLD PDYPRNISDG FDGIPDNVDA ALALPAHSYS GRERVYFFKG KQYWEYQFQH QPSQEECEGS SLSAVFEHFA MMQRDSWEDI FELLFWGRTS AGTRQPQFIS RDWHGVPGQV DAAMAGRIYI SGMAPRPSLA KKQRFRHRNR KGYRSQRGHS RGRNQNSRRP SRATWLSLFS SEESNLGANN YDDYRMDWLV PATCEPIQSV FFFSGDKYYR VNLRTRRVDT VDPPYPRSIA QYWLGCPAPG HL

Tag :

His-Tag

Expression System :

Baculovirus

Predicted nterm :

Ala

Product Type Name :

Recombinant Protein

UniProt No. :

P04004

Internal Search Terms :

Vitronectin, VitronectinVitronectin, VTN, V75, VN, VNT,ATGP3849-10ug,ATGP3849-20ug,ATGP3849-50ug,ATGP3849-100ug,ATGP3849-250ug,ATGP3849-500ug,ATGP3849-1mg,ATGP3849-10,ATGP3849-20,ATGP3849-50,ATGP3849-100,ATGP3849-250,ATGP3849-500,ATGP3849-1

more info or order :

NKMAX product webpage