product summary
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company name :
NKMAX
product type :
protein
product name :
Recombinant human EphB4 protein
catalog :
ATGP3843
quantity :
20 ug
price :
80 USD
more info or order :
product information
Product Type :
Proteins
Item Name :
Recombinant human EphB4 protein
Domain :
16-539aa
Catalog number (SKU) :
ATGP3843
NCBI :
NP_004435
Description :
EPHB4, also known ephrin type-B receptor 4, is a member of the Eph receptor tyrosine kinase family. It binds transmembrane ephrin-B family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. This protein plays a central role in heart morphogenesis and angiogenesis through regulation of cell adhesion and cell migration. And the signaling of this protein controls cellular repulsion and segregation form EFNB2-expressing cells. And it also plays a role in postnatal blood vessel remodeling, morphogenesis and permeability and is thus important in the context of tumor angiogenesis. Recombinant human EPHB4 protein, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Alternative Names :
Ephrin type-B receptor 4, EPHB4, HFASD, HTK, MYK1, TYRO11, EPH receptor B4, Hepatoma transmembrane kinase, Tyrosine-protein kinase TYRO11
Concentration :
0.25mg/ml (determined by absorbance at 280nm)
Formulation :
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Liu T., et al, (2017) Cell Physiol Biochem. 41:819-834.;;Kadife E., et al, (2018) Acta Oncol. 25:1-14.
Purity :
> 90% by SDS-PAGE
Applications :
SDS-PAGE
Antigen Species :
Human
Gene Category :
Cardiovascular
Molecular Weight :
58.1 kDa (532aa)
Endotoxin :
< 1 EU per 1ug of protein (determined by LAL method)
Amino Acid Sequence :
LEETLLNTKL ETADLKWVTF PQVDGQWEEL SGLDEEQHSV RTYEVCDVQR APGQAHWLRT GWVPRRGAVH VYATLRFTML ECLSLPRAGRSCKETFTVFY YESDADTATA LTPAWMENPY IKVDTVAAEH LTRKRPGAEA TGKVNVKTLR LGPLSKAGFY LAFQDQGACM ALLSLHLFYK KCAQLTVNLT RFPETVPREL VVPVAGSCVV DAVPAPGPSP SLYCREDGQW AEQPVTGCSC APGFEAAEGN TKCRACAQGT FKPLSGEGSC QPCPANSHSN TIGSAVCQCR VGYFRARTDP RGAPCTTPPS APRSVVSRLN GSSLHLEWSA PLESGGREDL TYALRCRECR PGGSCAPCGG DLTFDPGPRD LVEPWVVVRG LRPDFTYTFE VTALNGVSSL ATGPVPFEPV NVTTDREVPP AVSDIRVTRS SPSSLSLAWA VPRAPSGAVL DYEVKYHEKG AEGPSSVRFL KTSENRAELR GLKRGASYLV QVRARSEAGY GPFGQEHHSQ TQLDESEGWR EQLAVEHHHH HH
Tag :
His-Tag
Expression System :
Baculovirus
Predicted nterm :
Leu16
Product Type Name :
Recombinant Protein
UniProt No. :
P54760
Internal Search Terms :
EPHB4, Ephrin type-B receptor 4, EPHB4, HFASD, HTK, MYK1, TYRO11,ATGP3843-10ug,ATGP3843-20ug,ATGP3843-50ug,ATGP3843-100ug,ATGP3843-250ug,ATGP3843-500ug,ATGP3843-1mg,ATGP3843-10,ATGP3843-20,ATGP3843-50,ATGP3843-100,ATGP3843-250,ATGP3843-500,ATGP3843-1
more info or order :
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.