Recombinant human JNK3/MAPK10 protein | NKMAX ATGP3837 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human JNK3/MAPK10 protein

catalog :

ATGP3837

quantity :

10 ug

price :

160 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human JNK3/MAPK10 protein

Domain :

1-464aa

Catalog number (SKU) :

ATGP3837

NCBI :

NP_620448

Description :

MAPK10, also known as mitogen-activated protein kinase 10, is a member of the MAP kinase family. This group of protein kinases includes at least 10 members that interact selectively with ATF2, Jun and Elk-i transcription factors. It acts as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This protein is a neuronal-specific form of c-Jun N-terminal kinases (JNKs). Through its phosphorylation and nuclear localization, this kinase plays regulatory roles in the signaling pathways during neuronal apoptosis. Also, expression of multiple JNK isoforms provides a mechanism for the generation of tissue-specific responses to the activation of the JNK signal transduction pathway. Recombinant human MAPK10, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Alternative Names :

Mitogen-activated protein kinase 10, MAPK10, JNK3, JNK3A, p493F12, p54bSAPK, PRKM10, SAPK1b

Concentration :

0.25mg/ml (determined by Bradford assay)

Formulation :

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 30% glycerol, 1mM DTT, 0.1mM PMSF

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Mohit AA., et al, (1995) Neuron 14:67-78.;;Gupta S., et al, (1996) EMBO J. 15:2760-2770.

Purity :

> 85% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Neuroscience

Molecular Weight :

53.4 kDa (470aa)

Endotoxin :

< 1 EU per 1ug of protein (determined by LAL method)

Amino Acid Sequence :

MSLHFLYYCS EPTLDVKIAF CQGFDKQVDV SYIAKHYNMS KSKVDNQFYS VEVGDSTFTV LKRYQNLKPI GSGAQGIVCA AYDAVLDRNV AIKKLSRPFQ NQTHAKRAYR ELVLMKCVNH KNIISLLNVF TPQKTLEEFQ DVYLVMELMD ANLCQVIQME LDHERMSYLL YQMLCGIKHL HSAGIIHRDL KPSNIVVKSD CTLKILDFGL ARTAGTSFMM TPYVVTRYYR APEVILGMGY KENVDIWSVG CIMGEMVRHK ILFPGRDYID QWNKVIEQLG TPCPEFMKKL QPTVRNYVEN RPKYAGLTFP KLFPDSLFPA DSEHNKLKAS QARDLLSKML VIDPAKRISV DDALQHPYIN VWYDPAEVEA PPPQIYDKQL DEREHTIEEW KELIYKEVMN SEEKTKNGVV KGQPSPSGAA VNSSESLPPS SSVNDISSMS TDQTLASDTD SSLEASAGPL GCCR

Tag :

His-Tag

Expression System :

Baculovirus

Predicted nterm :

Met

Product Type Name :

Recombinant Protein

UniProt No. :

P53779

Internal Search Terms :

MAPK10, Mitogen-activated protein kinase 10, MAPK10, JNK3, JNK3A, p493F12, p54bSAPK, PRKM10, SAPK1b,ATGP3837-10ug,ATGP3837-20ug,ATGP3837-50ug,ATGP3837-100ug,ATGP3837-250ug,ATGP3837-500ug,ATGP3837-1mg,ATGP3837-10,ATGP3837-20,ATGP3837-50,ATGP3837-100,ATGP3837-250,ATGP3837-500,ATGP3837-1

more info or order :

NKMAX product webpage