Recombinant human Cardiac Troponin I3/TNNI3 protein | NKMAX ATGP3835 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human Cardiac Troponin I3/TNNI3 protein

catalog :

ATGP3835

quantity :

10 ug

price :

240 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human Cardiac Troponin I3/TNNI3 protein

Domain :

1-210aa

Catalog number (SKU) :

ATGP3835

NCBI :

NP_000354.4

Description :

TNNI3, also known as Troponin I3, is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TNNI3 is responsible for inhibition of actomyosin ATPase activity. Therefore, TNNI3 is a key regulatory protein in cardiac muscle contraction and relaxation cycle. Recently, specific missense mutations of the TNNI3 gene have been shown to cause familial hypertrophic cardiomyopathy. Recombinant human TNNI3 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by conventional chromatography.

Alternative Names :

Troponin I3, CMD1FF, CMD2A, CMH7, cTnl, RCM1, TNNC1

Concentration :

0.25mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 7.5) containing 30% glycerol, 0.1M NaCl, 0.1mM PMSF, 1mM DTT

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

DW Sohn., et al. (2017) Korean Circ J. 47(3):413-417.;;Elliot K., et al. (2000) J Biol Chem. 275(29):22069-74.;;

Purity :

> 90% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Cardiovascular

Molecular Weight :

26.4 kDa (233aa) confirmed by MALDI-TOF

Amino Acid Sequence :

MADGSSD AAREPRPAPA PIRRRSSNYR AYATEPHAKK KSKISASRKL QLKTLLLQIA KQELEREAEE RRGEKGRALS TRCQPLELAG LGFAELQDLC RQLHARVDKV DEERYDIEAK VTKNITEIAD LTQKIFDLRG KFKRPTLRRV RISADAMMQA LLGARAKESL DLRAHLKQVK KEDTEKENRE VGDWRKNIDA LSGMEGRKKK FES

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

P19429

Internal Search Terms :

Cardiac Troponin I, Troponin I3, CMD1FF, CMD2A, CMH7, cTnl, RCM1, TNNC1,ATGP3835-10ug,ATGP3835-20ug,ATGP3835-50ug,ATGP3835-100ug,ATGP3835-250ug,ATGP3835-500ug,ATGP3835-1mg,ATGP3835-10,ATGP3835-20,ATGP3835-50,ATGP3835-100,ATGP3835-250,ATGP3835-500,ATGP3835-1

more info or order :

NKMAX product webpage