Recombinant human FGF receptor 1/FGFR1 protein | NKMAX ATGP3828 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human FGF receptor 1/FGFR1 protein

catalog :

ATGP3828

quantity :

10 ug

price :

105 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human FGF receptor 1/FGFR1 protein

Domain :

22-285aa

Catalog number (SKU) :

ATGP3828

NCBI :

NP_075594

Description :

FGFR1b, also known as fibroblast growth factor receptor 1 isoform 4, is a member members of the fibroblast growth factor family. It is required for normal mesoderm patterning and correct axial organization during embryonic development, normal skeletogenesis and normal development of the gonadotropin-releasing hormone (GnRH) neuronal system. Tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of embryonic development, cell proliferation, differentiation and migration. Signaling of this protein is down-regulated by IL17RD/SEF, and by FGFR1 ubiquitination, internalization and degradation. Recombinant human FGFR1b protein, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Alternative Names :

Fibroblast growth factor receptor 1 isoform 1, FGFR-1, Basic fibroblast growth factor receptor 1, BFGFR, bFGF-R-1, Fms-like tyrosine kinase 2, FLT-2, N-sam, Proto-oncogene c-Fgr, CD331, CEK, FGFBR, FLG, HBGFR, KAL2, Pfeiffer syndrome

Concentration :

0.25mg/ml (determined by absorbance at 280nm)

Formulation :

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Lee JM., et al, (2008) Dev Biol. 314:341-350.;;Xu R., et al, (2013) FEBS J. 280:2260-2270.

Purity :

> 90% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Cardiovascular

Molecular Weight :

30.4 kDa (272aa)

Endotoxin :

< 1 EU per 1ug of protein (determined by LAL method)

Amino Acid Sequence :

RPSPTLPEQD ALPSSEDDDD DDDSSSEEKE TDNTKPNPVA PYWTSPEKME KKLHAVPAAK TVKFKCPSSG TPNPTLRWLK NGKEFKPDHR IGGYKVRYAT WSIIMDSVVP SDKGNYTCIV ENEYGSINHT YQLDVVERSP HRPILQAGLP ANKTVALGSN VEFMCKVYSD PQPHIQWLKH IEVNGSKIGP DNLPYVQILK TAGVNTTDKE MEVLHLRNVS FEDAGEYTCL AGNSIGLSHH SAWLTVLEAL EERPAVMTSP LYLELEHHHH HH

Tag :

His-Tag

Expression System :

Baculovirus

Predicted nterm :

Arg22

Product Type Name :

Recombinant Protein

UniProt No. :

P11362

Internal Search Terms :

FGF R1 Kinase Domain, Fibroblast growth factor receptor 1 isoform 4, FGFR1b, FGFR1, bFGF-R-1, BFGFR, CD331, CEK, ECCL, FGFBR, FGFR-1, FLG, FLT-2, FLT2, HBGFR, HH2, HRTFDS, KAL2, N-SAM, OGD,ATGP3828-10ug,ATGP3828-20ug,ATGP3828-50ug,ATGP3828-100ug,ATGP3828-250ug,ATGP3828-500ug,ATGP3828-1mg,ATGP3828-10,ATGP3828-20,ATGP3828-50,ATGP3828-100,ATGP3828-250,ATGP3828-500,ATGP3828-1

more info or order :

NKMAX product webpage