Recombinant human STAT3 protein | NKMAX ATGP3823 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human STAT3 protein

catalog :

ATGP3823

quantity :

10 ug

price :

150 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human STAT3 protein

Domain :

1-770aa

Catalog number (SKU) :

ATGP3823

NCBI :

NP_644805.1

Description :

STAT3, also known as signal transducer and activator of transcription 3 isoform 1, is a member of the STAT protein family. It is a transcription factor activated in response to cytokine, growth factor, or hormone receptor signaling. Once this protein is activated, recruits coactivators, such as NCOA1 or MED1, to the promoter region of the target gene and it mediates cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. It also acts as a regulator of inflammatory response by regulating differentiation of naive CD4+ T-cells into T-helper Th17 or regulatory T-cells. Recombinant human STAT3 protein, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Alternative Names :

Signal transducer and activator of transcription 3 isoform 1, STAT3, ADMIO, ADMIO1, APRF, HIES

Concentration :

0.25mg/ml (determined by absorbance at 280nm)

Formulation :

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 30% glycerol, 1mM DTT

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Chakraborty D., et al, (2017) Nat Commun. 8:1130.;;Han S., et al, (2018) Am J Cancer Res. 8:489-501.

Purity :

> 90% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Signal Transduction

Molecular Weight :

88.8 kDa (776aa)

Endotoxin :

< 1 EU per 1ug of protein (determined by LAL method)

Amino Acid Sequence :

MAQWNQLQQL DTRYLEQLHQ LYSDSFPMEL RQFLAPWIES QDWAYAASKE SHATLVFHNL LGEIDQQYSR FLQESNVLYQ HNLRRIKQFL QSRYLEKPME IARIVARCLW EESRLLQTAA TAAQQGGQAN HPTAAVVTEK QQMLEQHLQD VRKRVQDLEQ KMKVVENLQD DFDFNYKTLK SQGDMQDLNG NNQSVTRQKM QQLEQMLTAL DQMRRSIVSE LAGLLSAMEY VQKTLTDEEL ADWKRRQQIA CIGGPPNICL DRLENWITSL AESQLQTRQQ IKKLEELQQK VSYKGDPIVQ HRPMLEERIV ELFRNLMKSA FVVERQPCMP MHPDRPLVIK TGVQFTTKVR LLVKFPELNY QLKIKVCIDK DSGDVAALRG SRKFNILGTN TKVMNMEESN NGSLSAEFKH LTLREQRCGN GGRANCDASL IVTEELHLIT FETEVYHQGL KIDLETHSLP VVVISNICQM PNAWASILWY NMLTNNPKNV NFFTKPPIGT WDQVAEVLSW QFSSTTKRGL SIEQLTTLAE KLLGPGVNYS GCQITWAKFC KENMAGKGFS FWVWLDNIID LVKKYILALW NEGYIMGFIS KERERAILST KPPGTFLLRF SESSKEGGVT FTWVEKDISG KTQIQSVEPY TKQQLNNMSF AEIIMGYKIM DATNILVSPL VYLYPDIPKE EAFGKYCRPE SQEHPEADPG SAAPYLKTKF ICVTPTTCSN TIDLPMSPRT LDSLMQFGNN GEGAEPSAGG QFESLTFDME LTSECATSPM

Tag :

His-Tag

Expression System :

Baculovirus

Predicted nterm :

Met1

Product Type Name :

Recombinant Protein

UniProt No. :

P40763

Internal Search Terms :

STAT3, Signal transducer and activator of transcription 3 isoform 1, STAT3, ADMIO, ADMIO1, APRF, HIES,ATGP3823-10ug,ATGP3823-20ug,ATGP3823-50ug,ATGP3823-100ug,ATGP3823-250ug,ATGP3823-500ug,ATGP3823-1mg,ATGP3823-10,ATGP3823-20,ATGP3823-50,ATGP3823-100,ATGP3823-250,ATGP3823-500,ATGP3823-1

more info or order :

NKMAX product webpage