product summary
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company name :
NKMAX
product type :
protein
product name :
Recombinant human IL-2R beta/IL2RB protein
catalog :
ATGP3822
quantity :
10 ug
price :
105 USD
more info or order :
product information
Product Type :
Proteins
Item Name :
Recombinant human IL-2R beta/IL2RB protein
Domain :
27-240aa
Catalog number (SKU) :
ATGP3822
NCBI :
NP_000869.1
Description :
IL2RB, also known as interleukin 2 receptor subunit beta, is a member of the cytokine receptor superfamily. This protein, which is involved in T cell-mediated immune responses, is present in three forms with respect to ability to bind interleukin 2. It denoted IL2RA, IL2RB, and the common cytokine receptor gamma chain, which is shared by the receptors for IL-2, IL-4, IL-7, IL-9, and IL-15. The low affinity form is a monomer of the alpha subunit (also called CD25) and is not involved in signal transduction. The intermediate affinity form consists of a gamma/beta subunit heterodimer, while the high affinity form consists of an alpha/beta/gamma subunit heterotrimer. Both the intermediate and high affinity forms of the receptor are involved in receptor-mediated endocytosis and transduction of mitogenic signals from interleukin 2. Recombinant human IL2RB, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Alternative Names :
Interleukin-2 receptor subunit beta, IL-2 receptor subunit beta, IL-2R subunit beta, IL-2RB, High affinity IL-2 receptor subunit beta, Interleukin-15 receptor subunit beta, p70-75, p75, CD122, IL15RB, Interleukin 15 receptor beta
Concentration :
0.25mg/ml (determined by Bradford assay)
Formulation :
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Jounaidi Y., et al, (2017) Cancer Res. 77:5938-5951.;;Purvis SF., et al, (1992) Cell. Immunol. 144:32-42.
Purity :
> 95% by SDS-PAGE
Applications :
SDS-PAGE
Antigen Species :
Human
Gene Category :
Immunology
Molecular Weight :
25.5 kDa (220aa)
Endotoxin :
< 1 EU per 1ug of protein (determined by LAL method)
Amino Acid Sequence :
AVNGTSQFTC FYNSRANISC VWSQDGALQD TSCQVHAWPD RRRWNQTCEL LPVSQASWAC NLILGAPDSQ KLTTVDIVTL RVLCREGVRW RVMAIQDFKP FENLRLMAPI SLQVVHVETH RCNISWEISQ ASHYFERHLE FEARTLSPGH TWEEAPLLTL KQKQEWICLE TLTPDTQYEF QVRVKPLQGE FTTWSPWSQP LAFRTKPAAL GKDT
Tag :
His-Tag
Expression System :
Baculovirus
Predicted nterm :
Ala27
Product Type Name :
Recombinant Protein
UniProt No. :
P14784
Internal Search Terms :
IL2RB, Interleukin 2 receptor subunit beta, IL2RB, CD122, IL15RB, P70-75,ATGP3822-10ug,ATGP3822-20ug,ATGP3822-50ug,ATGP3822-100ug,ATGP3822-250ug,ATGP3822-500ug,ATGP3822-1mg,ATGP3822-10,ATGP3822-20,ATGP3822-50,ATGP3822-100,ATGP3822-250,ATGP3822-500,ATGP3822-1
more info or order :
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.