Recombinant human IL-18R alpha/IL18R1 protein | NKMAX ATGP3821 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human IL-18R alpha/IL18R1 protein

catalog :

ATGP3821

quantity :

10 ug

price :

80 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human IL-18R alpha/IL18R1 protein

Domain :

19-329aa

Catalog number (SKU) :

ATGP3821

NCBI :

NP_003846

Description :

IL18R1, also known as interleukin 18 receptor 1, is an interleukin receptor of the immunoglobulin superfamily. This protein contain three Ig-like C2-type (immunoglobulin-like) domains and on TIR domain. It shares numerous immuno-regulatory functions with IL12. IFN-alpha and IL12 are reported to induce the expression of this receptor in NK and T cells. Also, this receptor specifically binds interleukin 18 (IL18), and is essential for IL18 mediated signal transduction. It binds to the agonist leads to the activation of NF-kappa-B, but does not bind IL1A or IL1B beta. Recombinant human IL18R1, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Alternative Names :

Interleukin-18 receptor 1, CD218 antigen-like family member A, CDw218a, IL1 receptor-related protein, IL-1Rrp, IL1R-rp, Interleukin-18 receptor alpha, IL-18R-alpha, IL-18Ralpha, CD218a, IL1RRP, IL-1Rrp

Concentration :

0.5mg/ml (determined by absorbance at 280nm)

Formulation :

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Torigoe K., et al, (1997) J. Biol. Chem. 272:25737-25742.;;Hoshino K., et al, (1999) J. Immunol. 162:5041-5044.

Purity :

> 90% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Immunology

Molecular Weight :

62.7 kDa (550aa)

Endotoxin :

< 0.1 EU per 1ug of protein (determined by LAL method)

Amino Acid Sequence :

AESCTSRPHI TVVEGEPFYL KHCSCSLAHE IETTTKSWYK SSGSQEHVEL NPRSSSRIAL HDCVLEFWPV ELNDTGSYFF QMKNYTQKWK LNVIRRNKHS CFTERQVTSK IVEVKKFFQI TCENSYYQTL VNSTSLYKNC KKLLLENNKN PTIKKNAEFE DQGYYSCVHF LHHNGKLFNI TKTFNITIVE DRSNIVPVLL GPKLNHVAVE LGKNVRLNCS ALLNEEDVIY WMFGEENGSD PNIHEEKEMR IMTPEGKWHA SKVLRIENIG ESNLNVLYNC TVASTGGTDT KSFILVRKAD MADIPGHVFT RVEPKSCDKT HTCPPCPAPE LLGGPSVFLF PPKPKDTLMI SRTPEVTCVV VDVSHEDPEV KFNWYVDGVE VHNAKTKPRE EQYNSTYRVV SVLTVLHQDW LNGKEYKCKV SNKALPAPIE KTISKAKGQP REPQVYTLPP SRDELTKNQV SLTCLVKGFY PSDIAVEWES NGQPENNYKT TPPVLDSDGS FFLYSKLTVD KSRWQQGNVF SCSVMHEALH NHYTQKSLSL SPGKHHHHHH

Tag :

hIgG-His-Tag

Expression System :

Baculovirus

Predicted nterm :

Ala19

Product Type Name :

Recombinant Protein

UniProt No. :

Q13478

Internal Search Terms :

Interleukin-18 receptor alpha, Interleukin-18 receptor 1, Interleukin 18 receptor alpha, Interleukin 18 receptor 1, IL-1RRP, IL1R-rp, IL1RRP, IL-18R-alpha, IL-18Ralpha, IL-18R alpha, IL-1 receptor-related protein, IL1 receptor-related protein, IL-1 receptor related protein, IL1 receptor related protein, IL 1RRP, IL 18R alpha, IL 1 receptor-related protein, IL 1 receptor related protein, CDw218a, CD218a, CD218 antigen-like family member A, CD218 antigen like family member A, ATGP3821-10ug, ATGP3821-20ug, ATGP3821-50ug, ATGP3821-100ug, ATGP3821-250ug, ATGP3821-500ug, ATGP3821-1mg, ATGP3821-010, ATGP3821-020, ATGP3821-050, ATGP3821-100, ATGP3821-250, ATGP3821-500, ATGP3821-01M

more info or order :

NKMAX product webpage