Recombinant human HLA-DRB1 protein | NKMAX ATGP3818 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human HLA-DRB1 protein

catalog :

ATGP3818

quantity :

10 ug

price :

240 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human HLA-DRB1 protein

Domain :

30-227aa

Catalog number (SKU) :

ATGP3818

NCBI :

NP_002115

Description :

HLA-DRB1, also known as major histocompatibility complex, class II, DR beta 1 precursor, belongs to the human leukocyte antigen (HLA) class II beta chain paralogues. The class II molecule is a heterodimer consisting of an alpha (DRA) and a beta chain (DRB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins to T helper cells. It helps the immune system distinguish the body's own proteins from proteins made by foreign invaders such as viruses and bacteria. It is associated with an increased incidence of rheumatoid arthritis. Recombinant human HLA-DRB1, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Alternative Names :

Major histocompatibility complex, class II, DR beta 1, HLA-DRB1, DRB1, HLA-DR1B, HLA-DRB, SS1

Concentration :

0.25mg/ml (determined by absorbance at 280nm)

Formulation :

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 30% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

De Silvestri A., et al. (2017) Autoimmun Rev. 16:1230-1236.;;Riberdy JM., et al. (1992) Nature. 360:474-477.

Purity :

> 85% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Immunology

Molecular Weight :

24 kDa (207aa)

Endotoxin :

< 1 EU per 1ug of protein (determined by LAL method)

Amino Acid Sequence :

ADPGDTRPRF LWQPKRECHF FNGTERVRFL DRYFYNQEES VRFDSDVGEF RAVTELGRPD AEYWNSQKDI LEQARAAVDT YCRHNYGVVE SFTVQRRVQP KVTVYPSKTQ PLQHHNLLVC SVSGFYPGSI EVRWFLNGQE EKAGMVSTGL IQNGDWTFQT LVMLETVPRS GEVYTCQVEH PSVTSPLTVE WRARSESAQS KHHHHHH

Tag :

His-Tag

Expression System :

Baculovirus

Predicted nterm :

Ala

Product Type Name :

Recombinant Protein

UniProt No. :

Q29974

Internal Search Terms :

HLA-DRB1, Major histocompatibility complex, class II, DR beta 1, HLA-DRB1, DRB1, HLA-DR1B, HLA-DRB, SS1,ATGP3818-10ug,ATGP3818-20ug,ATGP3818-50ug,ATGP3818-100ug,ATGP3818-250ug,ATGP3818-500ug,ATGP3818-1mg,ATGP3818-10,ATGP3818-20,ATGP3818-50,ATGP3818-100,ATGP3818-250,ATGP3818-500,ATGP3818-1

more info or order :

NKMAX product webpage