Recombinant human sFRP-3/FRZB protein | NKMAX ATGP3815 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human sFRP-3/FRZB protein

catalog :

ATGP3815

quantity :

10 ug

price :

240 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human sFRP-3/FRZB protein

Domain :

33-325aa

Catalog number (SKU) :

ATGP3815

NCBI :

NP_001454

Description :

FRZB, also known as secreted frizzled-related protein 3, is a member of the family of Wnt-binding proteins with homology to the ligand binding domain of the Frizzled receptors. It is widely expressed in adult mammalian tissues and in chondrocytes. It is a key factors in blocking hypertrophic differentiation of human MSCs (hMSCs) and important in skeletal development in the embryo and fetus. It acts as an agonist of Wnt signaling and promotes invasive behavior. It has a role in regulating cell growth and differentiation in specific cell types. It also functions as a tumor suppressor in a variety of cancers. Recombinant human FRZB, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Alternative Names :

SRFP3, SFRP3, Secreted frizzled-related protein 3, OS1, hFIZ, FZRB, FRZB-PEN, FRZB1, FRZB, FRP-3, FRITZ, FRE

Concentration :

0.25mg/ml (determined by absorbance at 280nm)

Formulation :

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Zhong L1., et al. (2016) Stem Cells Dev. 25:1808-1817.;;Pecina-Slaus N1., et al. (2016) Mol Med Rep. 13:4245-4251.

Purity :

> 90% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Signal Transduction

Molecular Weight :

34.2 kDa (302aa)

Endotoxin :

< 1 EU per 1ug of protein (determined by LAL method)

Amino Acid Sequence :

ADPAACEPVR IPLCKSLPWN MTKMPNHLHH STQANAILAI EQFEGLLGTH CSPDLLFFLC AMYAPICTID FQHEPIKPCK SVCERARQGC EPILIKYRHS WPENLACEEL PVYDRGVCIS PEAIVTADGA DFPMDSSNGN CRGASSERCK CKPIRATQKT YFRNNYNYVI RAKVKEIKTK CHDVTAVVEV KEILKSSLVN IPRDTVNLYT SSGCLCPPLN VNEEYIIMGY EDEERSRLLL VEGSIAEKWK DRLGKKVKRW DMKLRHLGLS KSDSSNSDST QSQKSGRNSN PRQARNHHHH HH

Tag :

His-Tag

Expression System :

Baculovirus

Predicted nterm :

Ala

Product Type Name :

Recombinant Protein

UniProt No. :

Q92765

Internal Search Terms :

FRE, FRITZ, FRP 3, FRP3, FRP-3, FRZB, FRZB 1, FRZB1, FRZB-1, FRZB-PEN, FZRB, hFIZ, OS1, Secreted frizzled related protein 3, Secreted frizzled-related protein 3, SFRP 3, SFRP3, SFRP-3, SRFP 3, SRFP3, SRFP-3, ATGP3815-10ug, ATGP3815-20ug, ATGP3815-50ug, ATGP3815-100ug, ATGP3815-250ug, ATGP3815-500ug, ATGP3815-1mg, ATGP3815-010, ATGP3815-020, ATGP3815-050, ATGP3815-100, ATGP3815-250, ATGP3815-500, ATGP3815-01M

more info or order :

NKMAX product webpage