Recombinant human Angiogenin protein | NKMAX ATGP3811 product information

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product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human Angiogenin protein

catalog :

ATGP3811

quantity :

10 ug

price :

240 USD

product information

Product Type :

Proteins

Item Name :

Recombinant human Angiogenin protein

Domain :

25-147aa

Catalog number (SKU) :

ATGP3811

NCBI :

NP_001136

Description :

ANG, also known as angiogenin, is a potent stimulator of new blood vessels through the process of angiogenesis. It is a key protein implicated in angiogenesis in normal and tumor growth. This protein interacts with endothelial and smooth muscle cells resulting in cell migration, invasion, proliferation and formation of tubular structures. It binds to actin of both smooth muscle and endothelial cells to form complexes that activate proteolytic cascades which upregulate the production of proteases and plasmin that degrade the laminin and fibronectin layers of the basement membrane. Also, it exhibits ribonucleolytic activity that is distinctly different than that of pancreatic RNase A. This ribonucleolytic activity of ANG toward most RNase A substrates is much lower than that of RNase A. Recombinant human ANG, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Alternative Names :

Angiogenin, ANG, ALS9, HEL168, RAA1, RNASE4, RNASE5

Concentration :

0.25mg/ml (determined by Bradford assay)

Formulation :

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Shapiro R., et al, (1986) Biochemistry 25:3527-3532.;;Hooper LV., et al, (2003) Nat. Immunol. 4:269-273.

Purity :

> 90% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Signal Transduction

Molecular Weight :

15.2 kDa (132aa)ns)

Endotoxin :

< 1 EU per 1ug of protein (determined by LAL method)

Bioassay Procedure :

ADPQDNSRYT HFLTQHYDAK PQGRDDRYCE SIMRRRGLTS PCKDINTFIH GNKRSIKAIC ENKNGNPHRE NLRISKSSFQ VTTCKLHGGS PWPPCQYRAT AGFRNVVVAC ENGLPVHLDQ SIFRRPHHHH HH

Tag :

His-Tag

Expression System :

Baculovirus

Predicted nterm :

Ala

Product Type Name :

Recombinant Protein

UniProt No. :

P03950

Internal Search Terms :

Angiogenin, Angiogenin, ANG, ALS9, HEL168, RAA1, RNASE4, RNASE5,ATGP3811-10ug,ATGP3811-20ug,ATGP3811-50ug,ATGP3811-100ug,ATGP3811-250ug,ATGP3811-500ug,ATGP3811-1mg,ATGP3811-10,ATGP3811-20,ATGP3811-50,ATGP3811-100,ATGP3811-250,ATGP3811-500,ATGP3811-1