Recombinant human CD200R1 protein | NKMAX ATGP3809 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human CD200R1 protein

catalog :

ATGP3809

quantity :

10 ug

price :

120 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human CD200R1 protein

Domain :

24-243aa

Catalog number (SKU) :

ATGP3809

NCBI :

NP_740750

Description :

CD200R1, also known as cell surface glycoprotein CD200 receptor 1 isoform d, is a transmembrane protein in the immunoglobulin superfamily. This glycoprotein contains on C2 type Ig-like domain and V type Ig-like domain within its extracellular domain and a PTB-signaling motif in cytoplasmic domain. Also, it is expressed on myeloid cells and CD4+ T cells. For function, this receptor is restricted to the surfaces of myeloid lineage cells and the receptor-substrate interaction may function as a myeloid down regulatory signal. Activation of CD200R1 regulates the expression of inflammatory molecules such as tumor necrosis factor (TNF-alpha), interferon and inducible nitric oxide synthase (iNOS). Recombinant human CD200R1, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Alternative Names :

Cell surface glycoprotein CD200 receptor 1 isoform d, CD200 cell surface glycoprotein receptor, Cell surface glycoprotein OX2 receptor 1, CD200R, CRTR2, MOX2 receptor, MOX2R, OX2R, HCRTR2

Concentration :

0.25mg/ml (determined by absorbance at 280nm)

Formulation :

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Wright GJ., et al, (2003) J. Immunol. 171:3034-3046.;;Liu JQ., et al, (2016) J. Immunol. 197:1489-1497.

Purity :

> 90% by SDS-PAGE

Bioactivity Comment Only :

Measured by its binding ability in a functional ELISA with Human CD200 (CAT# ATGP4013). The ED50 range ≤ 1 ug/ml.

Applications :

SDS-PAGE, Bioactivity

Antigen Species :

Human

Gene Category :

Immunology

Molecular Weight :

51.9 kDa (462aa)

Endotoxin :

< 1 EU per 1ug of protein (determined by LAL method)

Bioactivity Comment and Pics :

CD200 (ATGP4013) is coated at 10 ug/ml (100 ul/well) can bind Human CD200R1. The ED50 range ≤ 1 ug/ml.

Amino Acid Sequence :

SSSLCMD EKQITQNYSK VLAEVNTSWP VKMATNAVLC CPPIALRNLI IITWEIILRG QPSCTKAYKK ETNETKETNC TDERITWVSR PDQNSDLQIR TVAITHDGYY RCIMVTPDGN FHRGYHLQVL VTPEVTLFQN RNRTAVCKAV AGKPAAHISW IPEGDCATKQ EYWSNGTVTV KSTCHWEVHN VSTVTCHVSH LTGNKSLYIE LLPVPGAKKS AKL

Tag :

hIgG-His-Tag

Expression System :

Baculovirus

Predicted nterm :

Ala

Product Type Name :

Recombinant Protein

UniProt No. :

Q8TD46

Internal Search Terms :

CD200R1, Cell surface glycoprotein CD200 receptor 1 isoform d, CD200R1, CD200R, HCRTR2, MOX2R, OX2R,ATGP3809-10ug,ATGP3809-20ug,ATGP3809-50ug,ATGP3809-100ug,ATGP3809-250ug,ATGP3809-500ug,ATGP3809-1mg,ATGP3809-10,ATGP3809-20,ATGP3809-50,ATGP3809-100,ATGP3809-250,ATGP3809-500,ATGP3809-1

more info or order :

NKMAX product webpage