product summary
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company name :
NKMAX
product type :
protein
product name :
Recombinant human IFN-gamma R1/IFNGR1 protein
catalog :
ATGP3807
quantity :
10 ug
price :
80 USD
more info or order :
product information
Product Type :
Proteins
Item Name :
Recombinant human IFN-gamma R1/IFNGR1 protein
Domain :
18-245aa
Catalog number (SKU) :
ATGP3807
NCBI :
NP_000407
Description :
IFNGR1, also known as interferon gamma receptor 1, is a member of the hematopoietic cytokine receptor superfamily. It is a receptor that binds interferon-gamma, the sole member of interferon type II. It induces the rapid dimerization of chains, thereby forming a site that is recognized by the extracellular domain of IFNGR2. It is expressed in a membrane-bound form in many cell types, and is over-expressed in tumour cells. Its signaling promotes autoimmune germinal centers via cell-intrinsic induction of BCL-6. It is crucial for host defence against mycobacterial infections. It is associated with susceptibility to pulmonary tuberculosis (TB). Recombinant human IFNGR1, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Alternative Names :
Interferon gamma receptor 1, IFNGR1, CD119, IFNGR, IMD27A, IMD27B, IFN-gamma receptor 1, CDw119, Interferon gamma receptor alpha-chain, IFN-gamma-R-alpha
Concentration :
1mg/ml (determined by absorbance at 280nm)
Formulation :
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Shamsi M., et al. (2016) Acta Microbiol Immunol Hung. 63:93-101.;;Bach EA., et al. (1997) Annu Rev Immunol. 15:563-591.
Purity :
> 90% by SDS-PAGE
Applications :
SDS-PAGE
Antigen Species :
Human
Gene Category :
Immunology
Molecular Weight :
26.6 kDa (234aa)
Endotoxin :
< 1 EU per 1ug of protein (determined by LAL method)
Amino Acid Sequence :
EMGTADLGPS SVPTPTNVTI ESYNMNPIVY WEYQIMPQVP VFTVEVKNYG VKNSEWIDAC INISHHYCNI SDHVGDPSNS LWVRVKARVG QKESAYAKSE EFAVCRDGKI GPPKLDIRKE EKQIMIDIFH PSVFVNGDEQ EVDYDPETTC YIRVYNVYVR MNGSEIQYKI LTQKEDDCDE IQCQLAIPVS SLNSQYCVSA EGVLHVWGVT TEKSKEVCIT IFNSSIKGHH HHHH
Tag :
His-Tag
Expression System :
Baculovirus
Predicted nterm :
Glu18
Product Type Name :
Recombinant Protein
UniProt No. :
P15260
Internal Search Terms :
IFN-g R1, Interferon gamma receptor 1, IFNGR1, CD119, IFNGR, IMD27A, IMD27B,ATGP3807-10ug,ATGP3807-20ug,ATGP3807-50ug,ATGP3807-100ug,ATGP3807-250ug,ATGP3807-500ug,ATGP3807-1mg,ATGP3807-10,ATGP3807-20,ATGP3807-50,ATGP3807-100,ATGP3807-250,ATGP3807-500,ATGP3807-1
more info or order :
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.